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LETTER TO THE EDITOR  
Year : 2013  |  Volume : 6  |  Issue : 3  |  Page : 378
Change of platelet count after receiving of garlic supplementation: An observation in cancerous patient


1 Food and Nutritional Supplementation Society; Physician Assistant Society, Thailand
2 Hainan Medical University, China

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Date of Web Publication7-Nov-2013
 

How to cite this article:
Chaiyasit K, Wiwanitkit V. Change of platelet count after receiving of garlic supplementation: An observation in cancerous patient. Ann Trop Med Public Health 2013;6:378

How to cite this URL:
Chaiyasit K, Wiwanitkit V. Change of platelet count after receiving of garlic supplementation: An observation in cancerous patient. Ann Trop Med Public Health [serial online] 2013 [cited 2020 Jan 23];6:378. Available from: http://www.atmph.org/text.asp?2013/6/3/378/121016
Dear Sir,

The garlic supplementation is mentioned for its usefulness in many medical disorders including to cardiovascular diseases and malignancies. [1] Focusing on the effect of garlic supplementation on platelet, it is reported for increasing platelet count in animal models. [2] On the other hand, the ajoene in garlic is mentioned for its opposite activity, antithrombotic activity. [3] The effect on a human is still controversial, and if it was used in human cases, the careful consideration is required. Here, the authors report the observed platelet count in a lung cancer patient after lobectomy for 3 years, without any other cancer therapy, who have garlic supplementation. The data of platelet count in this case before and after the garlic supplementation therapy is shown in [Table 1]. Here, the effect of garlic supplementation on platelet count can be seen. A significant reduction of platelet count can be seen, and this confirms the nature of antithrombotic activity. This can be useful in cancerous patient who has the trend to develop thrombosis.
Table 1: Platelet count of the patient

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   References Top

1.Butt MS, Sultan MT, Butt MS, Iqbal J. Garlic: Nature's protection against physiological threats. Crit Rev Food Sci Nutr 2009;49:538-51.  Back to cited text no. 1
    
2.Koga H, Tokunaga Y, Hisamoto T, Sujaku K, Mitsuyama K, Matsuo K, et al. Ratio of serum vascular endothelial growth factor to platelet count correlates with disease activity in a patient with POEMS syndrome. Eur J Intern Med 2002;13:70-74.  Back to cited text no. 2
    
3.Mousa SA. Antithrombotic effects of naturally derived products on coagulation and platelet function. Methods Mol Biol 2010;663:229-40.  Back to cited text no. 3
    

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Correspondence Address:
Kamon Chaiyasit
Food and Nutritional Supplementation Society, Thailand

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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1755-6783.121016

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