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Table of Contents   
LETTER TO THE EDITOR  
Year : 2015  |  Volume : 8  |  Issue : 4  |  Page : 150
Mycobacterium and sarcoidosis


1 Pokee-Clinic, Bangkok, Thailand
2 Hainan Medical University, Hainan, China

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Date of Web Publication7-Aug-2015
 

How to cite this article:
Pokee N, Wiwanitkit V. Mycobacterium and sarcoidosis. Ann Trop Med Public Health 2015;8:150

How to cite this URL:
Pokee N, Wiwanitkit V. Mycobacterium and sarcoidosis. Ann Trop Med Public Health [serial online] 2015 [cited 2019 Jun 26];8:150. Available from: http://www.atmph.org/text.asp?2015/8/4/150/162408
Dear Sir,

"Mycobacterium and sarcoidosis" is the present myth in tropical medicine. As noted by Bandyopadhyay et al., "the scientific evidence showing association of Mycobacterium and sarcoidosis is thought provoking in spite of some ambiguities." [1] Also, as noted by Piotrowski et al., "the co-incidence of tuberculosis (TB) and sarcoidosis, and higher incidence of mycobacterial DNA in biological samples of sarcoid patients, have been reported by many authors." [2] It is a challenge to answer the question whether Mycobacterium tuberculosis is a causative agent of sarcoidosis. In the recent report by Gupta et al., although there are some similarities, the difference in clinical features between TB and sarcoidosis can be observed. [3] Nevertheless, only the epidemiological observation or the observation on treatment outcome cannot bring about the conclusion. The proof that Mycobacterium tuberculosis can induce sarcoidosis must need a model to clarify the pathophysiological process, according to Koch's postulation. However, based on the present advent in bioinformatics, many new tools can be applied. For example, the proteomics technique might be used for protein identification in the cases with TB and sarcoidosis. Further, similarity comparison can be done. [4] In addition, comparative genomics might be helpful in finding the common gene and the biological processes identified in both diseases.

 
   References Top

1.
Bandyopadhyay D, Panchabhai TS, Mehta AC. Mycobacterium and sarcoidosis: Old wine in a new bottle. Lung India 2014;31:205-7.  Back to cited text no. 1
[PUBMED]  Medknow Journal  
2.
Piotrowski WJ, Górski P, Duda-Szymańska J, Kwiatkowska S. ­Mycobacterium tuberculosis as a sarcoid factor? A case report of family sarcoidosis. Am J Case Rep 2014;15:216-20.   Back to cited text no. 2
    
3.
Gupta D, Vinay N, Agarwal R, Agarwal AN. Socio-demographic profile of patients with sarcoidosis vis-à-vis tuberculosis. Sarcoidosis Vasc Diffuse Lung Dis 2013;30:186-93.  Back to cited text no. 3
    
4.
Chen ES, Moller DR. Expression profiling in granulomatous lung disease. Proc Am Thorac Soc 2007;4:101-7.  Back to cited text no. 4
    

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Correspondence Address:
Nora Pokee
Pokee-Clinic, Bangkok
Thailand
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1755-6783.162408

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