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ORIGINAL ARTICLE
Year : 2015  |  Volume : 8  |  Issue : 5  |  Page : 182-185

Association of lipid markers and impaired fasting glucose: A case-control study


1 Cardiovascular Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran
2 Faculty of health, Ilam University of Medical Sciences, Ilam, Iran
3 Kermanshah Health Research Center (KHRC), Kermanshah University of Medical Sciences, Kermanshah, Iran
4 University of Medical Sciences, Ilam, Iran

Correspondence Address:
Farid Najafi
Kermanshah Health Research Center (KHRC), Kermanshah University of Medical Sciences, Kermanshah
Iran
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Source of Support: Ilam University of Medical Sciences,, Conflict of Interest: None


DOI: 10.4103/1755-6783.162674

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Contexts: Association of lipid markers and occurrence of impaired fasting glucose (IFG) have a different pattern in different populations. Aims: The present study aimed to investigate the associations of some lipid markers with impaired fasting glucose in Kermanshah city, 2013. Settings and Designs: By a case-control study, 120 IFG subjects and 240 controls were recruited. Materials and Methods: Each subject was interviewed using a sociodemographic questionnaire and lipid markers including total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-c), high-density lipoprotein cholesterol (HDL-c), and fasting plasma glucose (FPG) were checked. Statistical Analysis Used: Chi-square test (χ 2 ), independent samples t-test, Pearson correlation coefficient, and a multiple logistic regression were used for statistical analyses. Results: IFG subjects had significantly higher TC, TG, and LDL-c than controls (P < 0.05) but both groups had comparable body mass index (BMI) and HDL-c, (P > 0.05). FPG was positively and significantly correlated with TG and TC ranges but not with BMI, LDL-c, and HDL-c. The highest correlation coefficients (r) with FPG was for TG rather than TC (r = 0.14, P < 0.01). In multivariable regression, the odds ratios (ORs) estimated for lipid markers were not associated with IFG but ORs in those females reported to have a history of oral contraceptive pill (OCP) usage was 2.4-fold compared to the controls [OR = 2.4, confidence interval (CI): 1.16-4.95]. Conclusions: TC, LDL-c, and TG had significantly higher values in IFG subjects and should be taken into consideration for the prevention of IFG.


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