Annals of Tropical Medicine and Public Health
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Year : 2016  |  Volume : 9  |  Issue : 5  |  Page : 360-361
Effect of tropical mushroom, Coriolus versicolor, on natural killer cell

1 Vital Life Center, Bumrungrad Hospital, Bangkok, Thailand
2 Department of Tropical Medicine, Hainan Medical University, Hainan, China

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Date of Web Publication12-Sep-2016

How to cite this article:
Chaiyasit K, Wiwanitkit V. Effect of tropical mushroom, Coriolus versicolor, on natural killer cell. Ann Trop Med Public Health 2016;9:360-1

How to cite this URL:
Chaiyasit K, Wiwanitkit V. Effect of tropical mushroom, Coriolus versicolor, on natural killer cell. Ann Trop Med Public Health [serial online] 2016 [cited 2020 Apr 6];9:360-1. Available from:
Dear Sir,

Several tropical mushrooms are mentioned for the clinical usefulness.

Coriolus versicolor is a species with some reports on its advantage in the human immune system. [1],[2],[3],[4] Here, the authors report observation on a patient with underlying breast cancer after complete standard treatment who intake C. versicolor as food supplementation. At first, her natural killer count (CD16/56) was at 5.9% (normal value 6.4-31.1). She got C. versicolor 2400 mg/day for 1 month, and the follow-up result showed CD16/56 equal to 11.6%. This observation can support the findings that C. versicolor could promote immunity.

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Conflicts of interest

There are no conflicts of interest.

   References Top

Hsieh TC, Wu JM. Regulation of cell cycle transition and induction of apoptosis in HL-60 leukemia cells by the combination of Coriolus versicolor and Ganoderma lucidum. Int J Mol Med 2013;32:251-7.  Back to cited text no. 1
Nicandro JP, Tsourounis C, Frassetto L, Guglielmo BJ. In vivo effect of I'm-Yunity on hepatic cytochrome P450 3A4. J Herb Pharmacother 2007;7:39-56.  Back to cited text no. 2
Hsieh TC, Wu P, Park S, Wu JM. Induction of cell cycle changes and modulation of apoptogenic/anti-apoptotic and extracellular signaling regulatory protein expression by water extracts of I'm-Yunity (PSP). BMC Complement Altern Med 2006;6:30.  Back to cited text no. 3
Hsieh TC, Kunicki J, Darzynkiewicz Z, Wu JM. Effects of extracts of Coriolus versicolor (I'm-Yunity) on cell-cycle progression and expression of interleukins-1 beta,-6, and -8 in promyelocytic HL-60 leukemic cells and mitogenically stimulated and nonstimulated human lymphocytes. J Altern Complement Med 2002;8:591-602.  Back to cited text no. 4

Correspondence Address:
Kamon Chaiyasit
Vital Life Center, Bumrungrad Hospital, Bangkok
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1755-6783.190205

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