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Table of Contents   
LETTER TO THE EDITOR  
Year : 2016  |  Volume : 9  |  Issue : 6  |  Page : 403-404
NS1 antigen and thrombocytopenia in dengue suspicious cases: An observation during dengue outbreak


1 TWS Primary Care Center, Bangkok, Thailand
2 Hainan Medical University, Haikou, Hainan, China

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Date of Web Publication14-Nov-2016
 

How to cite this article:
Sukkaromdee P, Wiwanitkit V. NS1 antigen and thrombocytopenia in dengue suspicious cases: An observation during dengue outbreak. Ann Trop Med Public Health 2016;9:403-4

How to cite this URL:
Sukkaromdee P, Wiwanitkit V. NS1 antigen and thrombocytopenia in dengue suspicious cases: An observation during dengue outbreak. Ann Trop Med Public Health [serial online] 2016 [cited 2017 Nov 22];9:403-4. Available from: http://www.atmph.org/text.asp?2016/9/6/403/193938
Dear Sir,

Dengue is the present health problem of tropical world. There are many thousand cases of dengue around the world every year. The big challenge is the early diagnosis of the cases.[1] Clinically, the physician usually diagnoses the cases when there are full blown clinical problems, hemorrhagic complication, and shock. The applications of new diagnostic tests have become the hope for early diagnosis and management of dengue. The dengue NS1 antigen test has been introduced as a diagnostic tool just for a few years.[2] In this study, the authors report the observation on NS1 antigen test result and thrombocytopenia (platelet count less than 100,000/µL) in dengue suspicious cases during a dengue outbreak in October 2015. In our medical center, the patients who presented acute febrile illness and had fever during visit to the hospitals in the dengue outbreak period were screened by complete blood count (CDC) and dengue NS1 antigen test. During the period, there were 284 dengue suspicious cases screened by CDC and dengue NS1 antigen tests. According to the screening, there were 101 dengue cases confirmed by NS1 antigen tests. The results are shown in [Table 1]. Based on this observation, it can be seen that 17 from 84 dengue cases have no thrombocytopenia. This can imply that if the physicians relied only on platelet count results for diagnosis of dengue, then there can be a 20.2% of under diagnosis.
Table 1: Results from laboratory investigations

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Conflicts of interest

There are no conflicts of interest.

 
   References Top

1.
Wiwanitkit V. Dengue fever: Diagnosis and treatment. Expert Rev Anti Infect Ther 2010;8:841-5.  Back to cited text no. 1
    
2.
Amorim JH, Alves RP, Boscardin SB, Ferreira LC. The dengue virus non-structural 1 protein: Risks and benefits. Virus Res 2014;181:53-60.  Back to cited text no. 2
    

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Correspondence Address:
Pathoom Sukkaromdee
TWS Primary Care Center, Bangkok
Thailand
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1755-6783.193938

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