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Table of Contents   
LETTER TO THE EDITOR  
Year : 2017  |  Volume : 10  |  Issue : 2  |  Page : 483-484
Peptide similarity, but no structure similarity: Can it explain the autoimmunity theory for pathology in Zika virus infection


1 RVT Medical Center, Bangkok, Thailand
2 Department of Tropical Medicine, Hainan Medical University, Hainan, China

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Date of Web Publication22-Jun-2017
 

How to cite this article:
Sriwijitalai W, Wiwanitkit V. Peptide similarity, but no structure similarity: Can it explain the autoimmunity theory for pathology in Zika virus infection. Ann Trop Med Public Health 2017;10:483-4

How to cite this URL:
Sriwijitalai W, Wiwanitkit V. Peptide similarity, but no structure similarity: Can it explain the autoimmunity theory for pathology in Zika virus infection. Ann Trop Med Public Health [serial online] 2017 [cited 2019 Oct 23];10:483-4. Available from: http://www.atmph.org/text.asp?2017/10/2/483/196858
Dear Sir,

Zika virus infection is the big problem at present. There is a new theory that autoimmunity leads to the main pathology in Zika virus infection. It is proposed that microcephaly and Guillain–Barré syndrome are important problems in Zika virus infection [1] Peptides' sharing is mentioned in that report.[1] However, hereby we further tried to predict the structure of the mentioned peptides using structural genomics and found that there is no structural similarity among the mentioned peptides. The explanation of the autoimmunity-based pathology in Zika virus infection is against this observation, and further study on this topic is recommended.

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Conflicts of interest

There are no conflicts of interest.

 
   References Top

1.
Lucchese G, Kanduc D. Zika virus and autoimmunity: From microcephaly to Guillain-Barré syndrome, and beyond. Autoimmun Rev 2016. pii: S1568-997230077-5.  Back to cited text no. 1
    

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Correspondence Address:
Won Sriwijitalai
RVT Medical Center, Bangkok
Thailand
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1755-6783.196858

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