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LETTER TO EDITOR  
Year : 2017  |  Volume : 10  |  Issue : 3  |  Page : 755
Reactome analysis of Zika virus genes: Implication for pathogenesis


1 Wiwanitkit House, Bangkhae, Bangkok, Thailand
2 Hainan Medical University, Hainan, China

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Date of Web Publication21-Aug-2017
 

How to cite this article:
Wiwanitkit S, Wiwanitkit V. Reactome analysis of Zika virus genes: Implication for pathogenesis. Ann Trop Med Public Health 2017;10:755

How to cite this URL:
Wiwanitkit S, Wiwanitkit V. Reactome analysis of Zika virus genes: Implication for pathogenesis. Ann Trop Med Public Health [serial online] 2017 [cited 2019 May 23];10:755. Available from: http://www.atmph.org/text.asp?2017/10/3/755/188507


Zika virus infection is the big present infectious threat.[1],[2] The exact pathophysiology of this infection needs further researches to clarify. Here, the authors report the observation on reactome analysis on the available Zika virus gene in database PubMED. The two available genes of Zika virus (ID: 7751225 and ID: 7751864) are used for reactome analysis using standard bioinformatics tool on Reactome Databse (www.reactome.org).[3],[4] Of interest, according to this analysis, there is no function of the genes in human beings. This implies that the studied Zika virus genes do not contribute any reactive pathway in human hosts. The pathology due to the virus should be due to the presently unidentified genes of the virus or immunopathology due to host reaction.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
   References Top

1.
Wang Z, Wang P, An J. Zika virus and Zika fever. Virol Sin 2016;31:103-9.  Back to cited text no. 1
    
2.
Joob B, Wiwanitkit V. Zika virus infection and dengue: A new problem in diagnosis in a dengue-endemic area. Ann Trop Med Public Health 2015;8:145-6.  Back to cited text no. 2
  [Full text]  
3.
Vastrik I, D'Eustachio P, Schmidt E, Gopinath G, Croft D, de Bono B, et al., Reactome: A knowledge base of biological pathways. Genome Biol 2007;8:R39.  Back to cited text no. 3
    
4.
Joshi-Tope G, Gillespie M, Vastrik I, D'Eustachio P, Schmidt E, de Bono B, et al., Reactome: A knowledge base of biologic pathways and processes. Nucleic Acids Res 2005;33:D428-32.  Back to cited text no. 4
    

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Correspondence Address:
Somsri Wiwanitkit
Wiwanitkit House, Bangkhae, Bangkok
Thailand
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1755-6783.188507

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