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Year : 2017  |  Volume : 10  |  Issue : 3  |  Page : 770-771
Can nocardiosis be isolated from ear discharge of otitis media patients? Yes or no

Health Management Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

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Date of Web Publication21-Aug-2017

How to cite this article:
Ali T. Can nocardiosis be isolated from ear discharge of otitis media patients? Yes or no. Ann Trop Med Public Health 2017;10:770-1

How to cite this URL:
Ali T. Can nocardiosis be isolated from ear discharge of otitis media patients? Yes or no. Ann Trop Med Public Health [serial online] 2017 [cited 2019 May 23];10:770-1. Available from:

Dear Sir,

Cholesteatomas is disease of the middle ear.[1] Its microbial etiology is unknown. However, it has to be said that different bacteria such as Pseudomonas aeruginosa, Staphylococcus aureus, Klebsiellasp., Proteussp., Alkaligenes spp., Streptococcus pneumoniae,  Escherichia More Details coli, and Citrobacter freundi and fungi Aspergillus niger, Candida albicans, Candida tropicalis, Aspergillus flavus, and Candida parasilopsis predominant bacteria was isolated causing otitis media anyway.[2] Nevertheless, no reports have shown that to isolation of Nocardia sp. related to otitis media especially in Cholesteatomas as an important diseases. Nocardia is a genus of weakly staining Gram-positive, catalase-positive, rod-shaped bacteria. It forms partially acid-fast beaded branching filaments (acting as fungi, but being truly bacteria). It contains a total of 85 species. Some species are nonpathogenic, while others are responsible for nocardiosis.[3] But little is known about relation between Nocardia sp. and otitis media or cholesteatomas. Nocardiosis is mainly referred to as the lung disease in immuncompormised patients, so no report has confirmed infection with ear with Nocardia sp. Nocardiosis of the middle ear has not been reported so far. The disease mainly with Cholesteatomas ignored in order to find out ateliology perhaps no microbial investigation were performed in order to find out the problem.[4] I would like to bring your attention in this letter to editor there are different factors in Cholesteatomas etiology, Nocardiosis may be doubtful as another microbial infection along with other micro-organism which mentioned above. Before and after Cholesteatomas surgery by surgeon in the patients ear discharge or fluid must be cultured by expert microbiologist in selective medium in order to find out the organisms. Perhaps Nocardia spp or other known or unknown organism may be added to known organisms anyway. Further studies will be shown the facts.

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There are no conflicts of interest.

   References Top

Konishi M, Iwai H, Tomoda K. Reexamination of Etiology and Surgical Outcome in Patient With Advanced External Auditory Canal Cholesteatoma. Otol Neurotol 2016;37:728-34.doi: 10.1097/MAO.0000000000001079.  Back to cited text no. 1
Ryan KJ, Ray CG. Sherris Medical Microbiology. 4th ed. McGraw Hill. 2004; 460-2.ISBN 0-8385-8529-9.  Back to cited text no. 2
Osazuwa F, Osazuwa E, Osime C, Igharo EA, Imade PE, Lofor P, Momoh M, Omoregie R, Dirisu J. Etiologic agents of otitis media in Benin city, Nigeria. N Am J Med Sci 2011;3:95-8.doi: 10.4297/najms.2011.395.  Back to cited text no. 3
Haarstad AC, Eisenschenk MC, Heinrich NA, Weese JS. McKeever PJ. Isolation of bacterial skin flora of healthy sheep, with comparison between frequent and minimal human handling. Vet Dermatol 2014;25:215-21.e55-6. doi: 10.1111/vde.12126.  Back to cited text no. 4

Correspondence Address:
Tavana Ali
Health Management Research Center, Baqiyatallah University of Medical Sciences, Tehran
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1755-6783.213153

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