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Year : 2017  |  Volume : 10  |  Issue : 4  |  Page : 1091-1092
Improvement of oral hygiene may be helped to gastric cancer reduction risk

Health Management Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

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Date of Web Publication5-Oct-2017

How to cite this article:
Tavana AM. Improvement of oral hygiene may be helped to gastric cancer reduction risk. Ann Trop Med Public Health 2017;10:1091-2

How to cite this URL:
Tavana AM. Improvement of oral hygiene may be helped to gastric cancer reduction risk. Ann Trop Med Public Health [serial online] 2017 [cited 2020 Apr 7];10:1091-2. Available from:

Dear Editor,

Nowadays, the improvement of oral health becomes an important because causes the reduction of heart diseases [1] and esophagus cancer risk.[2] But in this Letter to the Editor, I would like to mention about improvement of oral hygiene could be helped to reduction of gastric cancer or not? There are different factors related to gastric cancer (genetic, diet, stress, etc.). In another dimension, oral hygiene also related to many bacteria in particular Gram negative anaerobic bacteria (i.e., Porphyromonas spp, Prevotella spp, Fusobacterioum spp)[3],[4],[5],[6],[7] and other anerobic bacteria including: Actinomyces, Arachnia, Bifidobacterium, Eubacterium, Lactobacillus, Leptotrichia, Peptococcus, Peptostreptococcus, Propionibacterium, Selenomonas, Treponema, and Veillonella are involved.[8] However, the bacteria agent of gastric cancer is related to H. pylori.[9],[10] The isolation of H. pylori from oral cavity raised the question. Is there any role for H. pylori in oral disease with its virulence factors if so? Is it caused directly or indirectly effect in oral infections or not, if so, the first step to eradication of H. pylori is improvement of oral hygiene. Of course, different way may be related to H. pylori infection (fecal-oral, food-borne, waterborne, or even man-to-man transmission.[11],[12],[13],[14],[15] They also are important, but prevention of colonization in the body may be started from oral cavity.[16],[17],[18]

Thus, oral hygiene improving not only helps to provide good oral health for individual but also prevent many related diseases like heart disease, esophagus cancer, and defiantly gastric cancer. Health education oral health check-up and early treatment of any oral infections is recommended for all.



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   References Top

Tavana AM. Heart failure and oral bacteria: How could be prevented? J Cardiovasc Dis Res 2010;1:161.  Back to cited text no. 1
[PUBMED]  [Full text]  
Gao S, Li S, Ma Z, Liang S, Shan T, Zhang M, et al. Presence of Porphyromonas gingivalis in esophagus and its association with the clinicopathological characteristics and survival in patients with esophageal cancer. Infect Agent Cancer 2016;11:3. Doi:10.1186/s13027-016-0049-x.  Back to cited text no. 2
Finegold SM. Anaerobic infections in humans: An overview. Anaerobe 1995;1:3-9.  Back to cited text no. 3
Tavana AM, Drucker DB, Boote V. Phospholipid molecular species distribution of Porphyromonas asaccharolytica ATCC 25260T: Effects of temperature, culture age and pH. J Appl Microbiol 1998;85:1029-35.  Back to cited text no. 4
Drucker DB, Tavana AM, Boote V, Love DN. Is Porphyromonas gingivalis heterogeneous? Rev Med Microbiol 1997;8 (Suppl 1): S11-2.  Back to cited text no. 5
Tavana AM. Isolation of P. corporis from oral cavity: What is the role of this bacterium in the mouth and other parts of the human body? Indian J Dent Res 2009;20:129.  Back to cited text no. 6
Tavana AM. Still the role of Prevotella corporis in oral and nonoral diseases is not clear? Ann Trop Med Public Health [serial online] 2016. Available from: [Last accessed on 2016 May 10].  Back to cited text no. 7
Sutter VL. Anaerobes as normal oral flora. Rev Infect Dis 1984;6 (Suppl 1):S62-66. Doi:10.1093/clinids/6. Supplement_1.S62.  Back to cited text no. 8
Chen PY, Wu MS, Chen CY, Bair MJ, Chou CK, Lin JT, et al. Taiwan Gastrointestinal Disease and Helicobacter Consortium. Systematic review with meta-analysis: The efficacy of levofloxacin triple therapy as the first- or second-line treatments of Helicobacter pylori infection. Aliment Pharmacol Ther 2016;44:427-37. doi: 10.1111/apt.13712. Epub 2016 Jun 30.  Back to cited text no. 9
Veiga N, Pereira C, Resende C, Amaral O, Ferreira M, Nelas P. et al. Oral and gastric Helicobacter pylori: Effects and associations. PLoS One 2015;10:e0126923. doi: 10.1371/journal.pone.0126923. eCollection 2015.  Back to cited text no. 10
Bui D, Brown HE, Harris RB, Oren E. Serologic evidence for fecal-oral transmission of Helicobacter pylori. Am J Trop Med Hyg 2016;94:82-8. doi: 10.4269/ajtmh.15-0297.  Back to cited text no. 11
Rahimi E, Kheirabadi EK. Detection of Helicobacter pylori in bovine, buffalo, camel, ovine, and caprine milk in Iran. Foodborne Pathog Dis. 2012;9:453-6. doi: 10.1089/fpd.2011.1060.  Back to cited text no. 12
Travis PB, Goodman KJ, O'Rourke KM, Groves FD, Sinha D, Nicholas JS, et al. The association of drinking water quality and sewage disposal with Helicobacter pylori incidence in infants: The potential role of water-borne transmission. J Water Health 2010;8:192-203. doi: 10.2166/wh.2009.040.  Back to cited text no. 13
Wang XM, Yee KC, Hazeki-Taylor N, Li J, Fu HY, Huang ML, et al. Oral Helicobacter pylori, its relationship to successful eradication of gastric H. pylori and saliva culture confirmation. J Physiol Pharmacol 2014;65:559-66.  Back to cited text no. 14
Mach T. Is Helicobacter pylori infection a zoonosis? Przegl Lek. 2001;58:31-3. [Article in Polish].  Back to cited text no. 15
Sujatha S, Jalihal UM, Sharma S. Association between periodontal disease and oral and gastric Helicobacter pylori infection. Indian J Gastroenterol 2015;34:343-4. doi: 10.1007/s12664-015-0569-0  Back to cited text no. 16
Amiri N, Abiri R, Eyvazi M, Zolfaghari MR, Alvandi A. The frequency of Helicobacter pylori in dental plaque is possibly underestimated. Arch Oral Biol 2015;60:782-8. doi: 10.1016/j.archoralbio.2015.02.006.  Back to cited text no. 17
Tursi A, Cammarota G, Papa A, Cuoco L, Gentiloni N, Fedeli P, et al. The modes of transmission of Helicobacter pylori infection. Recenti Prog Med. 1997;88:232-6. [Article in Italian].  Back to cited text no. 18

Correspondence Address:
Ali Mehrabi Tavana
Health Management Research Center, Baqiyatallah University of Medical Sciences, Tehran
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1755-6783.196747

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