Annals of Tropical Medicine and Public Health

ORIGINAL ARTICLE
Year
: 2012  |  Volume : 5  |  Issue : 2  |  Page : 63--68

Clinico-radiological profile and treatment outcomes in neurocysticercosis: A study of 40 patients


Tushar B Patil1, Madhuri M Paithankar2 
1 Department of Medicine, MNR Medical College, Sangareddy, Andhra Pradesh, India
2 Department of Medicine, Government Medical College, Nagpur, Maharashtra, India

Correspondence Address:
Tushar B Patil
Plot No. 9, Rashtrasant Nagar, Godhani Road, Zingabai Takli, Nagpur - 440 030, Maharashtra
India

Aims: This study was aimed to study the clinical and radiological profile of neurocysticercosis and outcomes of treatment in neurocysticercosis. Settings and Design: A prospective observational study in a tertiary care hospital. Methods and Material: A total of 40 patients coming under definitive or probable diagnosis of neurocysticercosis as per the revised diagnostic criteria for neurocysticercosis were included in this study. Clinical history, physical examination, and neuroimaging (CT or MRI) studies were done at the beginning. Patients were treated with albendazole, corticosteroids, and antiepileptic drugs. They were followed up clinically for 3 months and neuroimaging study was repeated 3 months after albendazole therapy. Results: Definitive cases were 28 (70%) and probable cases were 12 (30%). Male: female ratio was 2.07. Mean age of 29.62 ± 9.08 years. The commonest presentation was seizures in 38 (95%). Twenty-nine (72.5%) patients had a single lesion and 11 (27.5%) had multiple lesions in initial imaging study. Commonest site of lesion was parietal lobe (45%). Most common stage of presentation was colloidal (55%). Thirty-seven (92.5%) patients were free of seizures at the end of three months. At the end of 3 months, 23 (57.5%) patients had radiological resolution (Complete resolution + partial resolution + calcification). Conclusions: Neurocysticercosis usually affects young persons, mostly in third decade, being equally common among vegetarians. Most common clinical manifestation is seizures. Single lesion is more common than multiple lesions, commonly presenting in colloidal. Clinical and radiological response to 4-week therapy with albendazole is quite satisfactory. All cases of young- and adult-onset epilepsy in tropical countries should be investigated for neurocysticercosis.


How to cite this article:
Patil TB, Paithankar MM. Clinico-radiological profile and treatment outcomes in neurocysticercosis: A study of 40 patients.Ann Trop Med Public Health 2012;5:63-68


How to cite this URL:
Patil TB, Paithankar MM. Clinico-radiological profile and treatment outcomes in neurocysticercosis: A study of 40 patients. Ann Trop Med Public Health [serial online] 2012 [cited 2020 Aug 5 ];5:63-68
Available from: http://www.atmph.org/article.asp?issn=1755-6783;year=2012;volume=5;issue=2;spage=63;epage=68;aulast=Patil;type=0