Annals of Tropical Medicine and Public Health

LETTER TO THE EDITOR
Year
: 2013  |  Volume : 6  |  Issue : 3  |  Page : 378-

Change of platelet count after receiving of garlic supplementation: An observation in cancerous patient


Kamon Chaiyasit1, Viroj Wiwanitkit2,  
1 Food and Nutritional Supplementation Society; Physician Assistant Society, Thailand
2 Hainan Medical University, China

Correspondence Address:
Kamon Chaiyasit
Food and Nutritional Supplementation Society, Thailand




How to cite this article:
Chaiyasit K, Wiwanitkit V. Change of platelet count after receiving of garlic supplementation: An observation in cancerous patient.Ann Trop Med Public Health 2013;6:378-378


How to cite this URL:
Chaiyasit K, Wiwanitkit V. Change of platelet count after receiving of garlic supplementation: An observation in cancerous patient. Ann Trop Med Public Health [serial online] 2013 [cited 2020 Feb 28 ];6:378-378
Available from: http://www.atmph.org/text.asp?2013/6/3/378/121016


Full Text

Dear Sir,

The garlic supplementation is mentioned for its usefulness in many medical disorders including to cardiovascular diseases and malignancies. [1] Focusing on the effect of garlic supplementation on platelet, it is reported for increasing platelet count in animal models. [2] On the other hand, the ajoene in garlic is mentioned for its opposite activity, antithrombotic activity. [3] The effect on a human is still controversial, and if it was used in human cases, the careful consideration is required. Here, the authors report the observed platelet count in a lung cancer patient after lobectomy for 3 years, without any other cancer therapy, who have garlic supplementation. The data of platelet count in this case before and after the garlic supplementation therapy is shown in [Table 1]. Here, the effect of garlic supplementation on platelet count can be seen. A significant reduction of platelet count can be seen, and this confirms the nature of antithrombotic activity. This can be useful in cancerous patient who has the trend to develop thrombosis.{Table 1}

References

1Butt MS, Sultan MT, Butt MS, Iqbal J. Garlic: Nature's protection against physiological threats. Crit Rev Food Sci Nutr 2009;49:538-51.
2Koga H, Tokunaga Y, Hisamoto T, Sujaku K, Mitsuyama K, Matsuo K, et al. Ratio of serum vascular endothelial growth factor to platelet count correlates with disease activity in a patient with POEMS syndrome. Eur J Intern Med 2002;13:70-74.
3Mousa SA. Antithrombotic effects of naturally derived products on coagulation and platelet function. Methods Mol Biol 2010;663:229-40.