Annals of Tropical Medicine and Public Health

ORIGINAL ARTICLE
Year
: 2014  |  Volume : 7  |  Issue : 1  |  Page : 9--13

Predictors of acute bacterial meningitis among children with a first episode of febrile convulsion from Northern India: A prospective study


Amiraj Singh, Joginder Silayach, Geeta Gathwala, Jaya Shankar Kaushik 
 Department of Paediatrics, Pt. B. D. Sharma Postgraduate Institute of Medical Sciences, Rohtak, Haryana, India

Correspondence Address:
Jaya Shankar Kaushik
Department of Paediatrics, Pt. B. D. Sharma Postgraduate Institute of Medical Sciences, Rohtak, Haryana - 124 001
India

Context: There is limited data to support need of lumbar puncture among Indian children aged less than 5 years presenting with a first episode of fever and seizure. Aims: To determine the incidence and clinical predictors of meningitis among children aged 6-60 months presenting with a first episode of febrile convulsion. Settings and Designs: A prospective study was conducted on 35 children (6-60 months) with a first episode of febrile convulsion subjected to lumbar puncture in a tertiary care teaching hospital of North India. Materials and Methods: Clinical characteristics were compared between the two groups: Children with meningitis (n = 17) and children without meningitis (n = 18). Statistical Methods: Multivariate logistic regression was applied to assess the independent predictors of meningitis. Results: A total of 120 children were screened; 35 children subjected to lumbar puncture were finally enrolled. The mean (SD) age of enrolled children was 18.49 (10.79) months. The incidence of meningitis was 48.6% (17/35). Children with meningitis significantly had a higher proportion of children with high grade (temperature >104°F) fever (P = 0.005), received prior antibiotics (P = 0. 041), had lower hemoglobin levels (P = 0.04) and lower blood sugar levels (P = 0.03) as compared to children with no meningitis. On multivariate logistic regression, it was observed that high-grade fever was an independent predictor of meningitis (odds ratio: 0.03 [0.001-0.86] [P = 0.04]). Conclusion: We found that the presence of high-grade fever was an important predictor of meningitis among children aged 6-60 months presenting with a first episode of febrile convulsion.


How to cite this article:
Singh A, Silayach J, Gathwala G, Kaushik JS. Predictors of acute bacterial meningitis among children with a first episode of febrile convulsion from Northern India: A prospective study.Ann Trop Med Public Health 2014;7:9-13


How to cite this URL:
Singh A, Silayach J, Gathwala G, Kaushik JS. Predictors of acute bacterial meningitis among children with a first episode of febrile convulsion from Northern India: A prospective study. Ann Trop Med Public Health [serial online] 2014 [cited 2019 Dec 9 ];7:9-13
Available from: http://www.atmph.org/article.asp?issn=1755-6783;year=2014;volume=7;issue=1;spage=9;epage=13;aulast=Singh;type=0