Annals of Tropical Medicine and Public Health

LETTER TO THE EDITOR
Year
: 2015  |  Volume : 8  |  Issue : 4  |  Page : 145--146

Zika virus infection and dengue: A new problem in diagnosis in a dengue-endemic area


Beuy Joob1, Viroj Wiwanitkit2,  
1 Sanitation 1 Medical Academic Center, Bangkok, Thailand
2 Hainan Medical University, Haikou, China; University of Nis, Serbia; Joseph Ayobabalola University, Nigeria; Dr. DY Patil Medical University, India

Correspondence Address:
Beuy Joob
Sanitation 1 Medical Academic Center, Bangkok, Thailand




How to cite this article:
Joob B, Wiwanitkit V. Zika virus infection and dengue: A new problem in diagnosis in a dengue-endemic area.Ann Trop Med Public Health 2015;8:145-146


How to cite this URL:
Joob B, Wiwanitkit V. Zika virus infection and dengue: A new problem in diagnosis in a dengue-endemic area. Ann Trop Med Public Health [serial online] 2015 [cited 2019 Nov 18 ];8:145-146
Available from: http://www.atmph.org/text.asp?2015/8/4/145/162402


Full Text

Dear Sir,

Zika is an important new emerging viral infection. [1] It is classified as a Flavivirus, and has a great similarity to other mosquito-borne infections. [1],[2] It has been recently included in the list of new emerging infectious diseases to be focused on. [2] Interestingly, the clinical manifestation of Zika virus infection is greatly similar to dengue, the most common arboviral infection in the tropical world. Due to the common clinical presentation, problems regarding the missed diagnosis and underdiagnosis of Zika virus infection in an endemic area of dengue can be expected. Interestingly, in a dengue-endemic area, the presumptive diagnosis of dengue is usually done without a standard confirmed diagnosis. In some cases, the use of immunoglobulin M (IgM) serology test is used for the diagnosis of dengue in a certain setting. [3] In addition, the false positive to dengue IgM serological test can be seen in Zika virus infection. Hence, it can be expected that there are many cases of Zika virus infection circulating in an endemic area of dengue without a proven diagnosis and in cases of a misdiagnosis of dengue. Interestingly, there are some recent reports on an imported case of Zika virus infection in Europe and on tracing history, it has been shown that the primary origin of this infection is from dengue-endemic areas such as Thailand. [3],[4]

References

1Hayes EB. Zika virus outside Africa. Emerg Infect Dis 2009; 15:1347-50.
2Barboza P, Tarantola A, Lassel L, Mollet T, Quatresous I, Paquet C. Emerging viral infections in South East Asia and the Pacific region. Med Mal Infect 2008;38:513-23.
3Fonseca K, Meatherall B, Zarra D, Drebot M, MacDonald J, Pabbaraju K, et al. First case of Zika virus infection in a returning Canadian traveler. Am J Trop Med Hyg 2014;91:1035-8.
4Tappe D, Rissland J, Gabriel M, Emmerich P, Gunther S, Held G, et al. First case of laboratory-confirmed Zika virus infection imported into Europe, November 2013. Euro Surveill 2014;19. pii: 20685.