Annals of Tropical Medicine and Public Health

LETTER TO EDITOR
Year
: 2017  |  Volume : 10  |  Issue : 3  |  Page : 755-

Reactome analysis of Zika virus genes: Implication for pathogenesis


Somsri Wiwanitkit1, Viroj Wiwanitkit2,  
1 Wiwanitkit House, Bangkhae, Bangkok, Thailand
2 Hainan Medical University, Hainan, China

Correspondence Address:
Somsri Wiwanitkit
Wiwanitkit House, Bangkhae, Bangkok
Thailand




How to cite this article:
Wiwanitkit S, Wiwanitkit V. Reactome analysis of Zika virus genes: Implication for pathogenesis.Ann Trop Med Public Health 2017;10:755-755


How to cite this URL:
Wiwanitkit S, Wiwanitkit V. Reactome analysis of Zika virus genes: Implication for pathogenesis. Ann Trop Med Public Health [serial online] 2017 [cited 2019 Aug 18 ];10:755-755
Available from: http://www.atmph.org/text.asp?2017/10/3/755/188507


Full Text



Zika virus infection is the big present infectious threat.[1],[2] The exact pathophysiology of this infection needs further researches to clarify. Here, the authors report the observation on reactome analysis on the available Zika virus gene in database PubMED. The two available genes of Zika virus (ID: 7751225 and ID: 7751864) are used for reactome analysis using standard bioinformatics tool on Reactome Databse (www.reactome.org).[3],[4] Of interest, according to this analysis, there is no function of the genes in human beings. This implies that the studied Zika virus genes do not contribute any reactive pathway in human hosts. The pathology due to the virus should be due to the presently unidentified genes of the virus or immunopathology due to host reaction.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

References

1Wang Z, Wang P, An J. Zika virus and Zika fever. Virol Sin 2016;31:103-9.
2Joob B, Wiwanitkit V. Zika virus infection and dengue: A new problem in diagnosis in a dengue-endemic area. Ann Trop Med Public Health 2015;8:145-6.
3Vastrik I, D'Eustachio P, Schmidt E, Gopinath G, Croft D, de Bono B, et al., Reactome: A knowledge base of biological pathways. Genome Biol 2007;8:R39.
4Joshi-Tope G, Gillespie M, Vastrik I, D'Eustachio P, Schmidt E, de Bono B, et al., Reactome: A knowledge base of biologic pathways and processes. Nucleic Acids Res 2005;33:D428-32.