LETTER TO THE EDITOR
Year : 2017 | Volume
: 10 | Issue : 4 | Page : 1081--1082
Nuclear-expressed sequence Tag (NEST) analysis of Zika virus nonstructural protein 1: Transciptomics approach
Somsri Wiwanitkit1, Viroj Wiwanitkit2,
1 Wiwanitkit House, Bangkhae, Bangkok, Thailand
2 Hainan Medical University, Hainan, China
Wiwanitkit House, Bangkhae, Bangkok
|How to cite this article:|
Wiwanitkit S, Wiwanitkit V. Nuclear-expressed sequence Tag (NEST) analysis of Zika virus nonstructural protein 1: Transciptomics approach.Ann Trop Med Public Health 2017;10:1081-1082
|How to cite this URL:|
Wiwanitkit S, Wiwanitkit V. Nuclear-expressed sequence Tag (NEST) analysis of Zika virus nonstructural protein 1: Transciptomics approach. Ann Trop Med Public Health [serial online] 2017 [cited 2019 Oct 19 ];10:1081-1082
Available from: http://www.atmph.org/text.asp?2017/10/4/1081/196696
Zika virus is a flavivirus of interest in the present day. Due to the emerging problem due to Zika virus infection, the study on virus sequences is very interesting in tropical biomedicine. Finding of the nuclear expressed sequence that is directly related to transcription process can be useful for target drug searching.
Here, the authors perform nuclear-expressed sequence Tag (NEST) analysis of Zika virus nonstructural protein 1. The technique is a transcriptomics approach as described by Macas et al. Based on the analysis, there are three identified positions within Zika virus nonstructural protein 1, Ser304(A), Gly305(A), and Arg306(A). These can be the focused sites for study on transcription of the virus and can be useful for further antiviral drug research.
Financial support and sponsorship
Conflicts of interest
There are no conflicts of interest.
|1||Macas J, Lambert GM, Dolezel D, Galbraith DW. Nuclear expressed sequence Tag (NEST) analysis: a novel means to study transcription through amplification of nuclear RNA. Cytometry 1998;33:460-8.|
|2||Kiechle FL, Holland-Staley CA. Genomics, transcriptomics, proteomics, and numbers. Arch Pathol Lab Med 2003;127:1089-97.|