Annals of Tropical Medicine and Public Health

LETTER TO THE EDITOR
Year
: 2017  |  Volume : 10  |  Issue : 4  |  Page : 1081--1082

Nuclear-expressed sequence Tag (NEST) analysis of Zika virus nonstructural protein 1: Transciptomics approach


Somsri Wiwanitkit1, Viroj Wiwanitkit2,  
1 Wiwanitkit House, Bangkhae, Bangkok, Thailand
2 Hainan Medical University, Hainan, China

Correspondence Address:
Somsri Wiwanitkit
Wiwanitkit House, Bangkhae, Bangkok
Thailand




How to cite this article:
Wiwanitkit S, Wiwanitkit V. Nuclear-expressed sequence Tag (NEST) analysis of Zika virus nonstructural protein 1: Transciptomics approach.Ann Trop Med Public Health 2017;10:1081-1082


How to cite this URL:
Wiwanitkit S, Wiwanitkit V. Nuclear-expressed sequence Tag (NEST) analysis of Zika virus nonstructural protein 1: Transciptomics approach. Ann Trop Med Public Health [serial online] 2017 [cited 2019 Oct 19 ];10:1081-1082
Available from: http://www.atmph.org/text.asp?2017/10/4/1081/196696


Full Text



Zika virus is a flavivirus of interest in the present day. Due to the emerging problem due to Zika virus infection, the study on virus sequences is very interesting in tropical biomedicine. Finding of the nuclear expressed sequence that is directly related to transcription process can be useful for target drug searching.[1]

Here, the authors perform nuclear-expressed sequence Tag (NEST) analysis of Zika virus nonstructural protein 1. The technique is a transcriptomics approach as described by Macas et al.[2] Based on the analysis, there are three identified positions within Zika virus nonstructural protein 1, Ser304(A), Gly305(A), and Arg306(A). These can be the focused sites for study on transcription of the virus and can be useful for further antiviral drug research.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

References

1Macas J, Lambert GM, Dolezel D, Galbraith DW. Nuclear expressed sequence Tag (NEST) analysis: a novel means to study transcription through amplification of nuclear RNA. Cytometry 1998;33:460-8.
2Kiechle FL, Holland-Staley CA. Genomics, transcriptomics, proteomics, and numbers. Arch Pathol Lab Med 2003;127:1089-97.