Annals of Tropical Medicine and Public Health

LETTER TO THE EDITOR
Year
: 2017  |  Volume : 10  |  Issue : 4  |  Page : 1090--1091

Thunbergia laurifolia, liver enzyme, and paracetamol


Kamon Chaiyasit1, Viroj Wiwanitkit2,  
1 Complementary Cancer Center, Vitallife at Bumrungrad International Hospital, Bangkok, Thailand
2 Joseph Ayobabalola University, Ikeji-Arakeji, Nigeria

Correspondence Address:
Kamon Chaiyasit
Complementary Cancer Center, Vitallife at Bumrungrad International Hospital, Bangkok
Thailand




How to cite this article:
Chaiyasit K, Wiwanitkit V. Thunbergia laurifolia, liver enzyme, and paracetamol.Ann Trop Med Public Health 2017;10:1090-1091


How to cite this URL:
Chaiyasit K, Wiwanitkit V. Thunbergia laurifolia, liver enzyme, and paracetamol. Ann Trop Med Public Health [serial online] 2017 [cited 2020 Apr 1 ];10:1090-1091
Available from: http://www.atmph.org/text.asp?2017/10/4/1090/196746


Full Text



Thunbergia laurifolia is a tropical plant that has been used as traditional herb for centuries. At present, it is used widely in Southeast Asia. Some reports mention that this herb can be useful for hepatoprotection and can make a recovery of liver impairment from injury by either infection or chemicals.[1],[2],[3] Here, the authors report on an interesting observation on a Thai male patient with fatty liver and chronic active hepatitis (ALP > 50 U/l for more than 1 year). The results of the blood test from a private laboratory showed AST of 28 U/l and ALT of 64 U/l. He had the self-prescribed local made T. laurifolia capsule (300 mg/capsule, three capsules per day). Three days later, the patient developed upper respiratory tract infection and took self-prescribed paracetamol at the highest recommended dosage for 4 days. After that, the patient still continued T. laurifolia capsule for additional 3 days and visited the laboratory again for the blood test, which showed AST of 28 U/l and ALT of 44 U/l. This report can be an evidence that T. laurifolia is a safe herb for patients with underlying fatty liver and hepatitis and can be concomitantly used with paracetamol. In addition, the reduction of ALT in this case can confirm the advantage of T. laurifolia on the liver.

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Conflicts of interest

There are no conflicts of interest.

References

1Wonkchalee N, Boonmars T, Laummaunwai P, Aromdee C, Hahnvajanawong C, Wu Z, et al. A combination of praziquantel and the traditional medicinal plant Thunbergia laurifolia on Opisthorchis viverrini infection and cholangiocarcinoma in a hamster model. Parasitol Res 2013;112:4211-9.
2Wonkchalee O, Boonmars T, Aromdee C, Laummaunwai P, Khunkitti W, Vaeteewoottacharn K, et al. Anti-inflammatory, antioxidant and hepatoprotective effects of Thunbergia laurifolia Linn. on experimental opisthorchiasis. Parasitol Res 2012;111:353-9.
3Pramyothin P, Chirdchupunsare H, Rungsipipat A, Chaichantipyuth C. Hepatoprotective activity of Thunbergia laurifolia Linn. extract in rats treated with ethanol: in vitro and in vivo studies. J Ethnopharmacol 2005;102:408-11.