Annals of Tropical Medicine and Public Health

ORIGINAL ARTICLE
Year
: 2017  |  Volume : 10  |  Issue : 6  |  Page : 1792--1798

The relationship of digestive system diseases in pregnant women with stillbirth and neonatal death in Iran: A population-based case–control study


Halimeh Yaghoobi1, Fatemeh Zolfizadeh2, Tannaz Valadbeigi3, Maryam Soltani4, Hamid Reza Tabatabaee5, Ali Reza Mirahmadizadeh5, Sepideh Mahdavi6, Abdolhalim Rajabi7, Ali Ghasemi8, Naeimeh Kevghobadi9, Cirrus Salehnasab10, Mahmoud Hajipour11 
1 MSc of Epidemiology, Social Determinants in Health Promotion Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Hormozgan, Iran
2 MSc of Health Care Management, Mother and Child Welfare Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
3 Department of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran
4 MSc of Epidemiology, School of Public Health, Mashhad University of Medical Sciences, Mashhad, Iran
5 Department of Epidemiology, Research Center for Health Sciences, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran
6 MSc of Epidemiology, Department of Epidemiology, School of Public Health, Shahroud University of Medical Sciences, Shahroud, Iran
7 Department of Epidemiology, Faculty of Health, Iran University of Medical Sciences, Tehran, Iran
8 Vice-chancellery of Health, Birjand University of Medical Sciences, Birjand, Iran
9 Department of Biostatistics Epidemiology, Health Faculty, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
10 Determinant of Health Research Center, Yasuj University of Medical Sciences, Yasuj, Iran
11 Department of Epidemiology, Research Center Office, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Correspondence Address:
Hamid Reza Tabatabaee
Department of Epidemiology, Research Center for Health Sciences, School of Health, Shiraz University of Medical Sciences, Shiraz
Iran

Background: The most important digestive system diseases implicated in pregnant mothers' stillbirth and neonatal death include large intestine diseases, Crohn's disease, ulcerative colitis, and stomach problems. This study aimed to determine the relationship between digestive system diseases in pregnant women and stillbirth and neonatal death. Methods: This population-based case-control study was conducted on 3573 mothers (1223 mothers experiencing stillbirth, 1091 mothers with neonatal death, and 1259 mothers with live births) in 10 provinces of Iran. The study data were analyzed using logistic regression analysis. Results: A total of 461 pregnant women (12.9%) suffered from digestive system diseases before the last pregnancy among whom 171 women (14.1%) experienced stillbirth, 149 (13.7%) reported neonatal deaths, and 141 women (11.2%) were in the control group. The results showed that the women with digestive system diseases were more likely (32%) to experience stillbirth when compared to those with no digestive system diseases (odds ratio [OR]: 1.32; 95% confidence interval [CI] [1.008 − 1.74]). Neonatal mortality was also higher (58%) among the mothers with digestive system diseases as compared to the control group (OR: 1.58, 95% CI [1.19 − 2.09]). Conclusion: Pregnant mothers with digestive system diseases were exposed to higher risks of severe prenatal consequences. The odds of stillbirth and neonatal death, were, respectively, 0.32 and 0.58 times higher in the pregnant mothers affected by digestive system diseases than those without such problems. This shows the undesirable effects of digestive system diseases on the fetus. Mothers' knowledge of appropriate nutrition and digestive system diseases has to be improved to prevent these consequences.


How to cite this article:
Yaghoobi H, Zolfizadeh F, Valadbeigi T, Soltani M, Tabatabaee HR, Mirahmadizadeh AR, Mahdavi S, Rajabi A, Ghasemi A, Kevghobadi N, Salehnasab C, Hajipour M. The relationship of digestive system diseases in pregnant women with stillbirth and neonatal death in Iran: A population-based case–control study.Ann Trop Med Public Health 2017;10:1792-1798


How to cite this URL:
Yaghoobi H, Zolfizadeh F, Valadbeigi T, Soltani M, Tabatabaee HR, Mirahmadizadeh AR, Mahdavi S, Rajabi A, Ghasemi A, Kevghobadi N, Salehnasab C, Hajipour M. The relationship of digestive system diseases in pregnant women with stillbirth and neonatal death in Iran: A population-based case–control study. Ann Trop Med Public Health [serial online] 2017 [cited 2019 Aug 18 ];10:1792-1798
Available from: http://www.atmph.org/article.asp?issn=1755-6783;year=2017;volume=10;issue=6;spage=1792;epage=1798;aulast=Yaghoobi;type=0