Annals of Tropical Medicine and Public Health
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STUDENT SECTION
Year : 2016  |  Volume : 9  |  Issue : 2  |  Page : 137-139

Small colony variants and their clinical significance


Department of Microbiology, Prathima Institute of Medical Sciences, Karimnagar, Telangana, India

Correspondence Address:
Venkataramana Venkataramana
Department of Microbiology, Prathima Institute of Medical Sciences, Karimnagar - 505 417, Telangana
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1755-6783.177406

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Among the many factors that contribute to bacterial colonization, persistence and development of infection, the ability of microorganisms to form small colony variants (SCVs) assumes great significance. Although bacteria require intrinsic virulence factors to cause pathogenesis, some of them regularly evolve mechanisms to evade immune mechanisms, become resistant to antibiotics, and sustain in the human/animal cells to cause chronic infections. This mini review highlights the recent advances in the study of SCVs.


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