Annals of Tropical Medicine and Public Health
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Year : 2017  |  Volume : 10  |  Issue : 6  |  Page : 1448-1452

Atypical manifestations of dengue fever in a recent dengue outbreak

Department of Medicine, Maulana Azad Medical College and Lok Nayak Hospital, NewDelhi, India

Correspondence Address:
Tanisha Kalra
A-407/Mahindra Appts, Vikas Puri, New Delhi - 110 018
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ATMPH.ATMPH_18_17

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Context: Dengue fever is highly prevalent in tropical and subtropical regions. The disease is caused by RNA virus, flavivirus and is transmitted by a mosquito to humans. Aims: The aim is to study the various atypical manifestations that can occur in dengue fever. Settings and Design: The patients presenting with acute febrile illness from September to December 2015 were admitted in a tertiary care hospital of North India and were screened for dengue fever. Atotal of 141patients were screened for dengue fever out of which 61patients were positive for dengue fever. Adetailed history of each patient reporting to the hospital was taken followed by the general physical examination and systemic examination. Subjects and Methods: Complete blood count was performed in all patients and other investigations such as liver and kidney function test, chest X-ray, ultrasound, magnetic resonance imaging, and cerebrospinal fluid examination were done wherever required. Results: Atypical manifestations were present in 24 of 61patients who were diagnosed positive for dengue fever(39.3%). Acalculous cholecystitis was the most common manifestation(32.7%), followed by encephalitis(6.5%) and hepatitis(3.2%). Transverse myelitis, acute respiratory distress syndrome, and renal failure had a frequency of 1.6%. There was no mortality as none of the patients had DSS in our study. Liver function tests(alkaline phosphatase and aspartate aminotransferase) were deranged in most patients(52.4%) out of which only 3.2% had raised serum bilirubin levels. Hepatomegaly was present in 19.6% of patients, and splenomegaly was observed in 3.2% of the patients. Conclusions: Dengue fever this year had various atypical manifestations–acalculous cholecystitis having the maximum occurrence. Neurological manifestations were also present. Transverse myelitis which is a rare manifestation was also observed.

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