Annals of Tropical Medicine and Public Health

ORIGINAL ARTICLE
Year
: 2012  |  Volume : 5  |  Issue : 5  |  Page : 474--478

Ocular manifestations in human immunodeficiency virus/acquired immuno deficiency syndrome patients and their correlation with CD4+ T-lymphocyte count


Ram Lal Sharma1, Praveen Panwar1, Ravinder Gupta1, Ashok Sharma2, Kulbhushan Chaudhary1 
1 Department of Ophthalmology, IGMC, Shimla, Himachal Pradesh, India
2 Department of Medicine, IGMC, Shimla, Himachal Pradesh, India

Correspondence Address:
Ram Lal Sharma
Department of Ophthalmology, IGMC Shimla, Himachal Pradesh
India

Aim: To study the various ocular manifestations in HIV/AIDS patients and their correlation with CD4+ cell count. Materials and Methods: In this study, 125 HIV-positive patients were studied for ocular features of HIV in the Department of Ophthalmology and Department of Medicine, for a period of 1 year. Statistical Analysis: Correlation of ocular findings with CD4+ cell count was analyzed using the Chi-Square test and «SQ»P«SQ» valve was calculated at 95% confidence limit. Results: Out of 125 HIV-positive patients, 70 were men and 55 were women. Ninety-seven (78%) were in the age group of 21-40 years. Ocular findings were seen in 41(33%) patients. Heterosexual transmission was the most common risk factor 118(94%). HIV retinopathy was the most common ocular lesion in 19 patients (46%) followed by anterior uveitis in 4 patients (10%). Among systemic lesions, pulmonary tuberculosis was common in 27 (22%) patients followed by oral candidiasis in 15 (12%) patients. Out of 41 (33%) ocular finding positive patients, 35 (85%) had CD4+ cell count less than 200 cells/mm 3 . Conclusion: HIV retinopathy and opportunistic ocular infections were common in HIV/AIDS patients. Ocular lesions were more common when CD4+ cell count was less than 200 cells/mm 3 . All patients who had CD4+ cell count less than 200 cells/mm 3 must undergo complete ophthalmic checkup to rule out ocular lesions.


How to cite this article:
Sharma RL, Panwar P, Gupta R, Sharma A, Chaudhary K. Ocular manifestations in human immunodeficiency virus/acquired immuno deficiency syndrome patients and their correlation with CD4+ T-lymphocyte count.Ann Trop Med Public Health 2012;5:474-478


How to cite this URL:
Sharma RL, Panwar P, Gupta R, Sharma A, Chaudhary K. Ocular manifestations in human immunodeficiency virus/acquired immuno deficiency syndrome patients and their correlation with CD4+ T-lymphocyte count. Ann Trop Med Public Health [serial online] 2012 [cited 2021 Jan 24 ];5:474-478
Available from: https://www.atmph.org/article.asp?issn=1755-6783;year=2012;volume=5;issue=5;spage=474;epage=478;aulast=Sharma;type=0