Annals of Tropical Medicine and Public Health
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Year : 2011  |  Volume : 4  |  Issue : 2  |  Page : 126-127

Isoniazid-induced psychosis in a patient on DOTS therapy

1 Department of Medicine, ASCOMS and Hospitals, Jammu, J and K, India
2 Department of Chest Medicine and Tuberculosis, ASCOMS and Hospitals, Jammu, J and K, India

Correspondence Address:
Imran Masood
E-21, E block, PG Hostel, ASCOMS and Hospital, Sidhra, Jammu - 180 017, J and K
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1755-6783.85769

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Acute psychosis induced by INH, especially when given as part of the DOTS regimen, has a variable presentation, and should always be kept in mind in the differential diagnosis. The diagnosis becomes especially challenging when the patient has tubercular meningitis or some other neurological disease. Here we present a case report of a patient who after 2 days of INH therapy under the DOTS regimen developed acute psychosis that resolved only after discontinuation of the drug.

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