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ORIGINAL ARTICLE
Year : 2012  |  Volume : 5  |  Issue : 1  |  Page : 24-28

Zinc phosphide toxicities among patients of the University of Benin Teaching Hospital, Benin city, Nigeria: A 10 year experience


Department of Drug and Poison Information Centre, University of Benin Teaching Hospital, Benin City, Nigeria

Correspondence Address:
S E Aghahowa
Department of Pharmacy, Drug and Poison Information Centre, University of Benin Teaching Hospital, P.M.B 1111 Ugbowo, Benin-City
Nigeria
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1755-6783.92874

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Background: Due to the poor success rate associated with zinc phosphide ingestion, it became necessary to assess the incidence. Objective: To assess the incidence of zinc phosphide toxicities reported between June 2000 and June 2009 in the University of Benin Teaching Hospital, Benin City, Nigeria. Material and Method : Data were sourced from the archives of casualties of zinc phosphide poisoning. These were entered into a generated case data form after obtaining an ethical permission. Results: All the ages of the 23 casualties reported were within 37.74±13.20 years. The male-female ratio was 4.75:1. Nineteen [78.26%] died after reporting 13.52±11.34 hours following single ingestion. Twenty cases were due to suicidal tendencies; the most common reason given was because of frustration in life related to marital affairs. Among the three unintentional, two were accidental while the other was due to assassination. Postmortem was refused in all the patients that died. One attempted herbal medication. Oil and milk were the most frequent solvents used at home as first-aid care therapy. Three were unintentional. Nine came with empty sachets and containers brought by relatives. Sodium chloride intravenous infusion was the most frequently used. Duration of hospitalization was 13.38±15.60 hours. Intravenous ciprofloxacin and metronidazole were the most common antibiotics used. Oxygen was instituted in 78.26% of the victims during respiratory distress. One ate meal prepared from poisoned rodent and died after reporting. One had alcohol along with the Zinc Phosphide ingestion. Nine were reported at the drug and poison information centre. Conclusion: Attention is needed by all for proper regulation in the handling of poisons and related substances to reduce burden minimally.


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