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Table of Contents   
LETTER TO THE EDITOR  
Year : 2014  |  Volume : 7  |  Issue : 6  |  Page : 268-269
Neuraminidase inhibitor resistance of the isolated influenza virus: Analysis of 54-month data from Thailand


1 KMT Medical Center, Bangkok, Thailand
2 Hainan Medical University, Haikou, China; Joseph Ayo Babalola University, Nigeria; University of Nis, Nis, Serbia; Dr DY Patil Medical University, Pune, Maharashtra, India; Surin Rajabhat University, Surin, Thailand

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Date of Web Publication14-Apr-2015
 

How to cite this article:
Yasri S, Wiwanitkit V. Neuraminidase inhibitor resistance of the isolated influenza virus: Analysis of 54-month data from Thailand. Ann Trop Med Public Health 2014;7:268-9

How to cite this URL:
Yasri S, Wiwanitkit V. Neuraminidase inhibitor resistance of the isolated influenza virus: Analysis of 54-month data from Thailand. Ann Trop Med Public Health [serial online] 2014 [cited 2020 May 31];7:268-9. Available from: http://www.atmph.org/text.asp?2014/7/6/268/155023
Dear Sir,

Acute febrile illness due to influenza virus infection has become a public concern at present. The infection can be seen worldwide and is the focus of disease surveillance and control by the World Health Organization (WHO). An interesting issue regarding the influenza virus being now studied is the emergence of the drug-resistant strain. Drug-resistant influenza can be problematic and difficult to treat. [1] The monitoring of drug resistance is interesting in a laboratory. However, due to its high cost, it is not routinely done in the developing countries. Here, the authors tried to analyze the primary data in the official report from National Influenza Center, Thailand. [2] The neuraminidase inhibitor resistance test of the isolated influenza virus was performed within the period January 2009-May 2013. Within the study period (54 months), there were 1,600 isolations of interest, and 0.68% were neuraminidase inhibitor-resistant. Classified by subgroups, the resistance can be seen in 0%, 0%, 1.36%, and 99.55% of influenza B, H3N2, the newly emerging H1N1, and classical H1N1, respectively. It should be noted that this resistance can be seen in only the H1N1s. The rate in this report is higher than the rate observed in a single center in Thailand (which was about 0.31%). [3] This shows that the presently used neuraminidase inhibitor will be of little use in fighting H1N1 influenza in Thailand.

 
   References Top

1.
Hurt AC. The epidemiology and spread of drug resistant human influenza viruses. Curr Opin Virol 2014;8:22-9.  Back to cited text no. 1
    
2.
Thai Department of Medical Science. News Letter. Dept Med Sci Lett 2013;27:5.  Back to cited text no. 2
    
3.
Payungporn S, Poomipak W, Makkoch J, Rianthavorn P, Theamboonlers A, Poovorawan Y. Detection of oseltamivir sensitive/resistant strains of pandemic influenza A virus (H1N1) from patients admitted to hospitals in Thailand. J Virol Methods 2011;177:133-9.  Back to cited text no. 3
    

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Correspondence Address:
Sora Yasri
KMT Medical Center, Bangkok
Thailand
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1755-6783.155023

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