Annals of Tropical Medicine and Public Health
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Year : 2012  |  Volume : 5  |  Issue : 3  |  Page : 256-258

Unilateral blindness following sino-orbito-cranial aspergillosis in a diabetic

Department of Medicine, Unit 45/46A, National Hospital of Sri Lanka, Colombo, Sri Lanka

Correspondence Address:
Mitrakrishan C Shivanthan
8, Sri Vajirashrama Mawatha, Off Campbell Place, Colombo 10
Sri Lanka
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1755-6783.98632

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A 56-year-old diabetic female presented with acute onset blindness with ptosis and complete ophthalmoplegia of the right eye. CT scan of the head showed soft tissue swelling of the right orbital cavity contents with proptosis and the CSF examination revealed sterile pleocytosis. Ipsilateral sinus mucosal histology showed inflammatory changes on H&E staining and fungal staining with methenamine-silver showed typical fungal hyphae of aspergillosis. The infection cleared with a course of IV amphotericin B however blindness and ophthalmoplegia of the right eye were permanent.

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