Annals of Tropical Medicine and Public Health
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Year : 2015  |  Volume : 8  |  Issue : 4  |  Page : 88-93

Understanding oral cancer at molecular level: The new frontier

1 Department of Public Health Dentistry, Government Dental College and Hospital, Shimla, Himachal Pradesh, India
2 Department of Oral and Maxillofacial Surgery, Gurunanak Institute of Dental Science Research, Kolkata, West Bengal, India
3 Department of Oral Pathology and Microbiology, Government Dental College and Hospital, Shimla, Himachal Pradesh, India
4 Department of Conservative and Endodontic, Government Dental College and Hospital, Shimla, Himachal Pradesh, India
5 Department of Radiation Oncology, Regional Cancer Centre, IGMC, Shimla, Himachal Pradesh, India

Correspondence Address:
Kavita Manchanda
Manchanda Medical Stores, 65, The Mall, Shimla - 171 001, Himachal Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1755-6783.162314

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Oral cancer is one of the major threats to public health in developed as well as developing countries. Despite the current therapeutic modalities, which include the use of nonselective treatments (surgery, radiation, and chemotherapy), the mortality and morbidity rates still remain high due to delays in diagnosis and treatment. Thus, it is important to completely understand the molecular mechanism in the development of oral cancer to further develop more selective treatment. This review attempts to identify and understand the deregulated molecular pathways and related genes in oral carcinogenesis.

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