Best CBD Cream For Neuropathy Pain 2024: 6 Products You Should Try

What is CBD Cream for Neuropathy Pain: A Comprehensive Guide

CBD, short for Cannabidiol, is a derivative of the Cannabis Sativa plant. Unlike THC, which is commonly used as an illicit substance for recreational purposes, CBD has shown promising therapeutic potential in treating various health conditions. Recent research has focused on its ability to manage anxiety disorders and a range of psychiatric disorders.

However, studies have also demonstrated its effectiveness in relieving chronic pain in the muscles and joints associated with peripheral neuropathy and arthritis. When used topically in cream form, CBD is absorbed through the skin and interacts with the body’s endocannabinoid system. This complex system is composed of CB1 and CB2 receptors, which have distinct effects depending on how they are activated.

THC, the primary active ingredient in CBD, interacts with these receptors, inhibiting FAAH and reducing the breakdown of endocannabinoids in the body. This results in effects that can be felt throughout the body’s various systems, including the nervous system, which plays a vital role in the management of related disorders.

In summary, CBD cream can be an effective treatment for managing neuropathy pain. It is a safe and natural alternative to traditional painkillers that can cause adverse side effects. Additionally, it offers a non-invasive solution to chronic pain that can significantly improve patients’ quality of life.

What is Neuropathy Pain?

Individuals who suffer from peripheral neuropathy are acutely aware of how significantly it can impact their quality of life. The constant joint pain and stiffness can make even the most basic daily activities a painful experience. Sometimes, traditional topical treatments may not provide any relief. Pain can be a hindrance for many people, which is why they often search for ways to alleviate it.

Why CBD Cream?

Fortunately, the use of topical CBD creams has shown promise as an effective way to relieve pain, despite legal concerns surrounding CBD products. This brings up an important question: which CBD creams are the most effective for treating neuropathic pain?

   Test Winner
 CBDfx CBD Cream Image Table littleAspen Green Muscle Image little tableCharlottes Web Cream Image Table
ProductCBDfx CBD CreamAspen Green Muscle CreamCharlotte`s Web Ointment
Against pain
Against pain
Verified potency
Highly effective
Verified potency
Side EffectsNO side effectsNO side effectsNO side effects
Content50 ml60 ml40 g
Dosage1-3 times daily1-3 times daily1-3 times daily
Enough forDepends on usageDepends on usageDepends on usage
Price49,99 Dollar84,99 Dollar29,99 Dollar
 Buy now whiteBuy now whiteBuy now button Original Colour

Is it Safe to Use CBD Creams for Neuropathic Pain?

While some clinical trials suggest that CBD creams are well-tolerated by patients, the FDA has cautioned that consuming CBD can result in various adverse effects, such as changes in mood or alertness.

Furthermore, higher doses of CBD can lead to liver damage as the drug must compete with liver enzymes and interact with other medications such as blood thinners. However, it remains unclear whether these risks apply solely to ingestible CBD products like capsules or extend to any product that contains CBD.

  • Charlotte’s Web Arthritis Aches & Pain Relief Ointment 
  • Aspen Green Muscle Relief Cream 
  • CBDfx CBD Cream For Muscle & Joint
  • Verma Farms CBD Cream 
  • CBDMedic Aches and Pain Relief 
  • Medterra Pain Relief Cream 

Test Winner: Charlotte's Web Cream

​Test winner #1
Charlottes Web Cream Image
Charlotte’s Web Cream
  • Highly effective against pain
  • Ideal for sensitive skin
  • Natural ingredients

CBD cream has been shown to be effective in relieving neuropathy pain, but it’s important to note that not all CBD creams are specifically designed for this purpose. While some CBD creams are marketed specifically for neuropathy pain relief, others may be formulated for different types of pain, such as arthritis-related pain.

If you are looking to use CBD cream for neuropathy pain, it’s essential to choose a product that is specifically designed for this purpose to ensure the best results. It’s always a good idea to check the product label and consult with a healthcare provider before using any new treatment for neuropathy pain.

Product features:

Manufacturer: Stanley Brothers
Pros: Vegan friendly, ideal for sensitive skin, made with globally and locally sourced ingredients from nature
Cons: May not smell appealing to all consumers
Rating: ⭐⭐⭐⭐⭐

Second Place: Aspen Green

​Second #2
Aspen Green Cream image
Aspen Green Cream
  • Very effective
  • Natural ingredients
  • Non-GMO

Also, the Aspen Green Cream for pain is an effective and effective remedy. In our test, it therefore deserves second place, even if the price is higher than usual for the market segment. Apart from that, the preparation contains only natural ingredients and is therefore particularly gentle.

Product features:

Manufacturer: Aspen Green
Pros: Contains CBD (organic) from the United States, no plasticizers or synthetic ingredients
Cons: More expansive than comparable products
Rating: ⭐⭐⭐⭐

Third Place: CBDfx

Third #3
CBDfx CBD Cream Image
CBDfx CBD Cream
  • Effective against pain
  • Broad-spectrum CBD
  • Vegan-friendly

CBDfx CBD Cream for Muscle & Joint is an excellent choice for anyone looking to alleviate muscle and joint pain. Its powerful formula, which includes a high concentration of broad-spectrum CBD, along with menthol and white willow bark extract, provides quick and effective relief from discomfort.

Product features:

Manufacturer: CBD FX
Pros: Fast & effective, verified potency, 60-day customer satisfaction guarantee
Cons: Not everywhere available website
Rating: ⭐⭐⭐⭐

Fourth Place: Verma Farms

​Place 4#
Verma Farms CBD image
Verma Farms CBD
  • Unadulterated hemp from US
  • Save & effective
  • coconut and vanilla scented

Experience the soothing aroma of the Hawaiian islands with this fast-acting CBD cream, which not only provides relief from pain but also hydrates and nourishes your skin. The cream has a delightful fragrance that will transport your senses to a tropical paradise, while the CBD provides targeted relief for your body’s aches and pains. This cream is perfect for those looking for a natural, non-invasive way to manage their pain while also keeping their skin healthy and moisturized.

Product features:

Manufacturer: Verma Farms
Pros: Coconut/ Vanilla aroma, works fast, from US hemp
Cons: Not much info on the website
Rating: ⭐⭐⭐

Fifth Place: CBD Medic

Place 5#
CBD Medic Aches and pain relief image
CBD Medic Aches and Pain Relief
  • Fast effect
  • Against arthritis
  • Dermatologist tested

This tube of cream packs a powerful punch with 200mg of CBD hemp extract, providing long-lasting and natural relief from the pains of arthritis. The cream’s natural ingredients and CBD extract work together to penetrate deep into your skin and provide targeted relief right where you need it.

Additionally, this cream is made with natural ingredients and free from harmful chemicals, making it a safe and effective option for anyone looking for a natural way to manage their pain. By using this cream regularly, you can improve your overall quality of life and enjoy the things you love without being held back by pain.

In summary, this cream is an excellent choice for anyone looking for long-lasting, natural relief from the pains of arthritis. With its potent formula and natural ingredients, it offers targeted relief that penetrates deep into your skin to provide effective and natural pain relief.

Product features:

Manufacturer: CBDMedic
Pros: Hypoallergenic, fast & effective, blended with natural moisturizers
Cons: More or less more expansive than comparable products
Rating: ⭐⭐⭐

Sixth Place: Medterra

​Place 6#
Medterra Pain Relief Cream
Medterra Pain Relief Cream
  • High effective
  • Well tolerated
  • Natural ingredients only

This CBD cream is not only a great option for localized pain relief but has also been proven effective for a variety of other ailments. When absorbed into the skin, the CBD extract in this cream interacts with the endocannabinoid system in your body, which can help to alleviate pain, inflammation, and other symptoms.

One of the benefits of using a CBD cream is its ability to provide targeted relief right where you need it. By applying the cream directly to the affected area, you can ensure that the CBD extract is absorbed directly into your skin and works quickly to provide relief. This makes it an ideal option for anyone experiencing muscle soreness, joint pain, or other localized discomfort.

Product features:

Manufacturer: Medterra
Pros: Could potentially help with skin inflammation as well, natural ingredients, more affordable than other similar products
Cons: Not certified, no discount programs
Rating: ⭐⭐⭐

How To Use CBD Cream Against Neuropathy Pain?

Looking for a natural way to alleviate neuropathy pain? CBD creams can be a great option. Not only are they easy to use, but they also offer targeted relief by directly targeting the affected area. Using CBD cream is a breeze. All you need to do is apply it to your skin as you would any other topical product, such as lotion. When you apply it directly to the affected area, the skin absorbs the CBD and delivers it into the bloodstream.

It’s important to note that the pain-relieving effects of CBD can last between two to six hours. Therefore, it’s best to wait for that duration before applying it again. This will help ensure that you don’t apply too much CBD cream, which can cause adverse effects. In summary, using CBD cream for neuropathy pain is a straightforward process that can offer targeted relief. Just remember to wait for the effects to wear off before applying it again.

How You Choose The Best CBD Cream Against Neuropathy Pain?

If you’re considering using CBD cream for your neuropathy pain, it’s important to choose the right product. With so many options on the market, it can be overwhelming to decide which one will work best for you. One crucial factor to consider when selecting a CBD cream is the source of your pain. Some creams are specifically formulated for arthritic pain, while others are better suited for neuropathic pain.

It’s essential to read the product labels carefully and choose a cream that targets your specific type of pain. Another important consideration is your budget. The prices of CBD creams can vary widely, with some products costing as little as $30 and others as much as $85.

It’s crucial to determine how much you’re willing to spend before making a purchase. When it comes to selecting the best CBD cream for your neuropathy pain, it’s crucial to do your research and choose a product that meets your specific needs. With the right cream, you can experience targeted relief and improved quality of life.

Who Shoud Use CBD Cream?

CBD creams are a great option for those who suffer from muscle and joint pain caused by health conditions such as arthritis and peripheral neuropathy. These conditions can cause severe pain that affects daily life, and CBD creams can offer targeted relief.

However, CBD creams can also be helpful for those experiencing muscle and joint pain due to other ailments. It’s important to note that while there is evidence that CBD creams can reduce anxiety, they should not be used as the sole treatment for this condition. Those who suffer from anxiety should speak with their healthcare provider and consider other treatment options, such as medication.

It’s important to keep in mind that CBD products are only available to consumers over the age of 21. If you’re considering using CBD cream for your neuropathy pain, it’s essential to consult with your healthcare provider to determine if it’s the right option for you.

Benefits Of CBD Cream Against Neuropathy Pain

CBD cream has been shown to provide numerous benefits for those who suffer from neuropathy pain. Here are some of the most significant benefits:

Relieves Chronic Neuropathic Pain: CBD cream has been found to effectively relieve nerve pain and other unpleasant sensations in patients with symptomatic peripheral neuropathy. A study compared the effectiveness of CBD cream to a placebo, and the results showed that patients who used CBD cream experienced a significant improvement in pain relief, including the intensity and sharpness of the pain. The group that used CBD cream also reported a significant reduction in cold and itchy sensations. Importantly, no adverse effects were observed in either group.

Reduces Anxiety: There appears to be a link between the effects of CBD on pain relief and anxiety relief. The reduction in anxiety likely contributes to improving pain perception, while reduced pain perception can alleviate anxiety. A study found that patients with moderate to severe pain experienced significant improvement in anxiety levels upon using CBD. However, those with only mild pain did not experience the same level of improvement.

CBD cream is a natural and effective way to manage neuropathy pain. It offers targeted relief without the adverse effects that can come with traditional pain medications. If you’re interested in using CBD cream for neuropathy pain, it’s important to speak with your healthcare provider to determine if it’s the right option for you.


As CBD cream continues to gain popularity as a seemingly effective way to handle joint and muscle pain, prospective consumers may have some questions about how it works and how to use it. Here are some frequently asked questions and their answers:

How does CBD cream work?

CBD cream works by interacting with the endocannabinoid system (ECS) in the body. The ECS plays a crucial role in regulating various bodily functions such as pain, appetite, and sleep. When CBD is applied topically to the skin, it is absorbed into the nearby bloodstream, where it can interact with the ECS to reduce inflammation and pain.

Can CBD cream be used for all types of joint pain?

CBD creams can be used to relieve joint pain caused by a variety of conditions, including arthritis and peripheral neuropathy. However, it’s important to note that CBD cream may not be effective for all types of joint pain, and it’s always best to speak with a healthcare provider before using CBD cream to treat any condition.

Can CBD cream relieve neuropathy pain?

Yes, CBD cream has been shown to effectively relieve neuropathy pain in some patients. A study has highlighted how CBD creams can work to relieve nerve pain and other “disturbing sensations” in patients with symptomatic peripheral neuropathy.

How do I use CBD cream for neuropathy pain?

CBD cream is applied topically to the affected area of the skin, where it can be absorbed into the bloodstream and interact with the endocannabinoid system to reduce inflammation and pain. It is recommended to wait for two to six hours before reapplying the cream.

Are there any side effects of using CBD cream for neuropathy pain?

CBD cream is generally considered safe, and there are no significant side effects associated with its use. However, as with any medication or treatment, it is always best to consult with a healthcare provider before using CBD cream to treat neuropathy pain, especially if you have any underlying medical conditions or are taking other medications.


In conclusion, CBD cream is a promising option for treating neuropathy pain, and there are many different brands and manufacturers to choose from. However, deciding which one is right for you can be challenging. It’s essential to consider your individual needs and the underlying cause of your joint pain when selecting a CBD cream.

With the potential to relieve chronic neuropathic pain and reduce anxiety, CBD cream offers a natural and effective alternative to traditional pain medications. If you’re interested in trying CBD cream for neuropathy pain, be sure to speak with your healthcare provider to determine if it’s the right choice for you.

Paul Mies has now been involved with test reports and comparing products for a decade. He is a highly sought-after specialist in these areas as well as in general health and nutrition advice. With this expertise and the team behind, they test, compare and report on all sought-after products on the Internet around the topics of health, slimming, beauty and more. The results are ultimately summarized and disclosed to readers.