Annals of Tropical Medicine and Public Health
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Year : 2017  |  Volume : 10  |  Issue : 5  |  Page : 1260-1264

Evaluation of risk factors impact on cataract development for uranium industry workers

1 Chair of ENT and Eye Diseases, JSC Medical University of Astana, Astana, Republic of Kazakhstan
2 Institute of Radiobiology and Radiation Protection, JSC Medical University of Astana, Astana, Republic of Kazakhstan

Correspondence Address:
Zhibek S Dautbayeva
Chair of ENT and Eye Diseases, JSC Medical University of Astana, Beybitshilik, 49A, 010000 Astana
Republic of Kazakhstan
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ATMPH.ATMPH_175_17

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The abundance and rough relative risk of cataract among 544 workers at the hydrometallurgical plant of Stepnogorsk Mining and Chemical Combine, depending on the total integrated dose of external irradiation, taking into account non-radiation factors, was studied. The conducted studies showed a statistically significant high abundance of ophthalmic pathology, including cataracts among workers in the main group compared with the control group. A statistically significant trend in the increase of cataracts with an increase in the total integrated dose, smoking index of more than 20 packs/year, increase in body weight and persons suffering from hypertension. As a result of a multivariate analysis of risk factors connection to cataract, we revealed that the cumulative dose and length of exposure are the main indicators predicting the development of cataracts for uranium industry adult workers. It is known that age is a key risk factor for many diseases, including cataracts. Lens opacity is a pluricausal manifestation, which is based on the mechanism associated with the course of time.

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