Annals of Tropical Medicine and Public Health
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Year : 2010  |  Volume : 3  |  Issue : 1  |  Page : 35-38

Ethical issues in malaria vaccine clinical trials: A principle-based approach

1 Department of Medicine, Kogi State Specialist Hospital, Lokoja, Nigeria
2 Institute of Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria

Correspondence Address:
Joseph O Fadare
Department of Medicine, Kogi State Specialist Hospital, Lokoja
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1755-6783.76185

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Malaria remains a major problem with the significant public health dimension affecting hundreds of millions of people annually, mainly in sub-Saharan Africa. The effectiveness of the measures currently used to control the disease is now drastically reduced because of the development of parasite resistance to the anti-malarial drugs and vector adaptation to the insecticides. On account of this development, efforts are ongoing to develop a malaria vaccine to help in the prevention of the disease as well as in reducing the severity in patients. Drug research and development have always raised a lot of ethical issues, especially in the context of developing countries like those of sub-Saharan Africa. This article discusses some of these ethical dilemmas using a template based on the four principles of biomedical ethics.

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