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ORIGINAL ARTICLE
Year : 2012  |  Volume : 5  |  Issue : 5  |  Page : 479-482

Serum HSV-1 and 2 IgM in patients of sexually transmitted diseases


1 Department of Microbiology, Civil Hospital, Gandhinagar, India
2 Department of Microbiology, B. J. Medical College, Ahmedabad, Gujarat, India

Correspondence Address:
Dharmishtha G Tada
Department of Microbiology, Civil Hospital, Gandhinagar, Gujarat
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1755-6783.105138

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Background: Herpes simplex virus type1 & 2 (HSV 1 &2) are the causative agent for genital herpes. Aim: To examine Serum HSV-1 and 2 IgM in all type of STD (sexually transmitted disease) patients including Human immunodeficiency virus (HIV) infection and also to evaluate correlation of Serum HSV-1 and 2 IgM in these patients. Materials and Methods: 150 patients attending the STD clinic attached to a tertiary care hospital of Ahmedabad were included in the study. These all patients were screened for HIV-1 and 2 antibodies. Serum HSV-1 and 2 IgM correlations with HIV infection and clinical manifestations of genital herpes patients and other non herpetic STD patients were studied. Results: The overall Serum HSV-1 and 2 IgM in STD seroprevalence was 15.66%. Female have significant higher prevalence (p < 0.05). STD cases and HSV seroprevalence were specially concentrated in persons aged 21 to 30 years. Among those positive with HSV, the distribution of STD are wide spread and found in non herpetic group at high frequency. Out of total 23 Serum HSV-1 and 2 IgM positive, 5 (21.73%) were HIV reactive. Discussion and Conclusion: Though Serum HSV-1 and 2 IgM in sexually transmitted diseases is less diagnostic, it helps to see the iceberg part of the infection among the population concerned recently. Putting STD surveillance systems in place specially in areas with high prevalence of HIV will be crucial in monitoring changes so that appropriate adjustments can be made to treatment schedules to make them more cost effective.


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