Annals of Tropical Medicine and Public Health
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Year : 2013  |  Volume : 6  |  Issue : 1  |  Page : 47-49

A study on serological correlation of clinically suspected leptospirosis cases in West Bengal, India

1 Department of Microbiology, School of Tropical Medicine, Kolkata, India
2 Department of Tropical Medicine, School of Tropical Medicine, Kolkata, India

Correspondence Address:
Monalisa Majumdar
Department of Microbiology, School of Tropical Medicine, 108, CR Avenue, Kolkata - 700 073
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1755-6783.115186

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Context: Leptospirosis is a zoonotic infection with worldwide significance. It is caused by a spirochete Leptospira interrogans, which has many serogroups and a large number of serovars. Leptospirosis is an emerging public health problem in India. Aims: Leptospirosis is an emerging public health problem and keeping this in mind 216 clinically suspected cases of leptospirosis have been considered for serological study. Failure to recognize these cases leads to serious morbidity and mortality. Hence, the present study was undertaken to identify these cases by simple laboratory techniques so that timely management could be undertaken. Settings and Design: Hospital-based cross-sectional case control study. Subjects and Methods: Patients with unexplained fever for more than seven days with or without jaundice or renal failure were taken up for this study. IgM ELISA tests were performed with the serum samples of the patients. Statistical Analysis Used: Simple statistical methods applying Epi info. Results: Total 77 patients were found to be reactive for IgM ELISA. Total 100% of seropositive patients had fever and 40% had jaundice. Peak incidence of the disease was found in the period from July to November (monsoon and post-monsoon period). Male preponderance was seen and mainly urban population was found to be seropositive in our study. Conclusions: Seroprevalence of leptospirosis was found to be remarkable in our study; 35% of the clinically suspected patients showed positive IgM ELISA tests.

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