Annals of Tropical Medicine and Public Health
Home About us Ahead Of Print Instructions Submission Subscribe Advertise Contact e-Alerts Editorial Board Login 
Users Online:236
  Print this page  Email this page Small font sizeDefault font sizeIncrease font size
CASE REPORT
Year : 2013  |  Volume : 6  |  Issue : 3  |  Page : 343-344

Isolated immunoglobulin A (IgA) deficiency presenting with cytomegalo virus pneumonia


1 Department of Pediatrics, All India Institute of Medical Sciences, Bhopal, India
2 Department of Pediatrics, PGIMER, Dr. RML Hospital, New Delhi, India

Correspondence Address:
Jhuma Sankar
Department of Pediatrics, PGIMER, Dr. RML Hospital, New Delhi
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1755-6783.121003

Rights and Permissions

A 5-month-old infant with an uneventful perinatal period was presented with lower respiratory tract symptoms and abnormal X-ray findings of 1-month duration. At admission, the baby was in respiratory distress requiring oxygen therapy and supportive care. Despite optimal supportive care and antibiotic therapy, he continued to be symptomatic necessitating further investigations for nonresolving pneumonia. His bronchoalveolar lavage and urine were positive for cytomegalovirus (CMV) and workup for immunodeficiency showed undetectable immunoglobulin A(IgA) levels. Rest of the workup was inconclusive. We investigated the mother for a carrier status, but the workup was negative for CMV and/or other intrauterine infections. In view of severe CMV-associated lung disease, the baby was started on ganciclovir therapy for 6 weeks on which he recovered completely. Although the associated isolated IgA deficiency may be an incidental finding in this case, it is indeed intriguing and requires further research.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2051    
    Printed44    
    Emailed0    
    PDF Downloaded11    
    Comments [Add]    

Recommend this journal