Annals of Tropical Medicine and Public Health
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CASE REPORT
Year : 2016  |  Volume : 9  |  Issue : 4  |  Page : 271-272

Carbimazole induced atypia in the thyroid gland


Department of Pathology, Swami Ramanand Teerth Rural Government Medical College, Ambajogai, Maharashtra, India

Correspondence Address:
Sunil Y Swami
Bhagwanbaba Chowk, Gitta - Road, Shepwadi, Taluka: Ambajogai, District: Beed, Ambajogai - 431 517, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1755-6783.184784

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Thyroid nuclear atypia associated with carbimazole is well-known. However, there are rare cases described in literature. We report here a case of thyroid fine needle aspiration cytology (FNAC) of a follicular lesion of undetermined significance or nuclear atypia of undetermined significance (FLUS/AUS) observed in a 56-year-old female presenting with Hashimoto's thyroiditis on treatment by carbimazole. In conclusion, thyroid nuclear atypia in the form of anisonucleosis, prominent nucleoli, and hyperchromasia associated with carbimazole treatment should be interpreted with caution in differentiating from malignancy.


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