Annals of Tropical Medicine and Public Health
Home About us Ahead Of Print Instructions Submission Subscribe Advertise Contact e-Alerts Editorial Board Login 
Users Online:695
currentissue backissue special isse search   Print this page  Email this page Small font sizeDefault font sizeIncrease font size
 


 
Table of Contents   
LETTER TO EDITOR  
Year : 2017  |  Volume : 10  |  Issue : 3  |  Page : 755-756
Prenatal MRI in Zika Virus Infection


Visiting professor Hainan Medical University, China; Wiwanitkit House, Bangkhae, Bangkok, Thailand

Click here for correspondence address and email

Date of Web Publication21-Aug-2017
 

How to cite this article:
Wiwanitkit V. Prenatal MRI in Zika Virus Infection. Ann Trop Med Public Health 2017;10:755-6

How to cite this URL:
Wiwanitkit V. Prenatal MRI in Zika Virus Infection. Ann Trop Med Public Health [serial online] 2017 [cited 2019 May 23];10:755-6. Available from: http://www.atmph.org/text.asp?2017/10/3/755/213138


Dear Editor,

The prenatal diagnosis of brain abnormality due to Zika virus infection is an interesting issue in tropical medicine. The recent report by Guillemette-Artur et al.[1] on “prenatal brain MRI of fetuses with Zika virus infection” is very interesting. Guillemette-Artur et al.[1] found that “severe cerebral damage was observed in our series, with indirect findings suggesting that the germinal matrix is the principal target for Zika virus..” In fact, this finding is contrast to some previous reports. In a recent report by Cavalheiro et al.[2], it is noted that “there is a definitive pathognomonic radiographic pattern of microcephaly caused by Zika virus.” In addition, as noted by Guillemette-Artur et al.[1], the similar findings to that can be seen in cytomegalovirus infection is mentioned Indeed, the similarity can be expected, as both Zika virus and cytomegalovirus (CMV) can directly attack fetal brain tissue. However, there is an interesting observation, “gross” calcifications, that is not commonly observed in cases with cytomegalovirus infection.[3] In fact, although both Zika virus and CMV attack fetal brain tissue, accounting for similarities being expected regarding brain lesions, there might be argument. Parvovirus B19 and Toxoplasmosis also attack fetal brain tissue but are responsible for very different lesions due to mechanism being different. In CMV, gross or more subtle calcifications can be observed. Saying that the germinal matrix might be the principal target for Zika virus is not at all in contradiction with other reports and this hypothesis should be confirmed by further experiments.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest to declare.



 
   References Top

1.
Guillemette-Artur P, Besnard M, Eyrolle-Guignot D, Jouannic JM, Garel C. Prenatal brain MRI of fetuses with Zika virus infection. Pediatr Radiol 2016;46:(7)1032-9.  Back to cited text no. 1
    
2.
Cavalheiro S, Lopez A, Serra S, Da Cunha A, da Costa MD, Moron A, Lederman HM. Microcephaly and Zika virus: neonatal neuroradiological aspects. Childs Nerv Syst 2016;32:(6)1057-60.  Back to cited text no. 2
    
3.
Malinger G, Lev D, Lerman-Sagie T. Imaging of fetal cytomegalovirus infection. Fetal Diagn Ther 2011;29:117-26.  Back to cited text no. 3
    

Top
Correspondence Address:
Viroj Wiwanitkit
Wiwanitkit House, Bangkhae, Bangkok

Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1755-6783.213138

Rights and Permissions




 

Top
 
  Search
 
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Email Alert *
    Add to My List *


    References

 Article Access Statistics
    Viewed426    
    Printed6    
    Emailed0    
    PDF Downloaded18    
    Comments [Add]    

Recommend this journal