Annals of Tropical Medicine and Public Health
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Year : 2017  |  Volume : 10  |  Issue : 4  |  Page : 1058-1060

Salmonella typhi bacteriuria, predispositions and complications: Two case reports and review of literature

1 Department of Microbiology, Indraprastha Apollo Hospitals, New Delhi, India
2 Department of Nephrology, Indraprastha Apollo Hospitals, New Delhi, India
3 Department of Radiology, Indraprastha Apollo Hospitals, New Delhi, India

Correspondence Address:
Reetika Dawar
Department of Microbiology, Indraprastha Apollo Hospitals, Sarita Vihar, New Delhi - 110 076
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ATMPH.ATMPH_94_17

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Salmonella typhi infection presents most commonly as typhoid fever and infrequently as extraintestinal localized infections of bone, joints, soft tissues, spleen, endocardium, pulmonary, hepatobiliary, genital and urinary systems. Urinary tract infection ( UTI) is rare and clinical presentation is indistinguishable from UTIs due to other etiological agents or may even be asymptomatic. We report two cases of patients with chronic kidney disease with UTI due to S. typhi. Renal cyst, nephrolithiasis, and urethral strictures were the concomitant findings in one case and renal tubular acidosis with nephrocalcinosis in the other. In patients with relapses and a chronic course with coexisting functional or structural abnormalities of the urinary tract system, the suspicion of Salmonella as one of the probable causative agents should be kept in mind so as to ensure appropriate and adequate therapy. Furthermore, in the presence of long-standing hypokalemia, one should investigate for renal abnormalities and vice versa.

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