Annals of Tropical Medicine and Public Health
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Year : 2017  |  Volume : 10  |  Issue : 6  |  Page : 1496-1499

Prevalence of proteinuria and abnormal urinary cytology in HIV+ve asymptomatic patients

1 Department of Pathology, School of Tropical Medicine, All India Institute of Hygiene and Public Health, Kolkata, West Bengal, India
2 Department of Pathology, School of Tropical Medicine, All Institute of Hygiene and Public Health, Kolkata, West Bengal, India

Correspondence Address:
Sumana Mukherjee
BH-62, Sector-2, Salt Lake, Kolkata, West Bengal
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ATMPH.ATMPH_403_17

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Context: A variety of renal abnormalities have been described among HIV-infected patients leading to various clinical presentations. However, early renal disease in HIV+ve patients is asymptomatic. Aims: This study aims to detect the prevalence of proteinuria and abnormal urinary cytology in HIV-infected patients. Subjects and Methods: Atotal of 140patients asymptomatic for renal disease and HIV infected were tested for proteinuria(dipstick method), urinary cytology, CD4 count, and serum creatinine(to determine estimated glomerular filtration rate[eGFR]). Statistical Analysis: The data were analyzed using the Chi-square test and Fisher's exact probability test( Results: About 30.7% of patients were detected with proteinuria. Asignificant proportion of patients with proteinuria had low eGFR. Low CD4 count(<200) and age(≥40) were highly associated with presence of proteinuria. However, urinary cytology was not significantly associated with low eGFR, although abnormal eGFR was more common in the presence of abnormal urinary cytology. Conclusions: Asignificant proportion of HIV+ve patients asymptomatic for renal disease may have proteinuria(which is an indicator of nephropathy). The test for proteinuria is simple and therefore should be regularly done in all patients. Abnormal urinary cytology is relatively common in this group and should also be tested in all patients.

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