| ORIGINAL ARTICLE |
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| Year : 2010 | Volume
: 3
| Issue : 2 | Page : 58-63 |
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Clinico-radiological profile and treatment outcomes in neurocysticercosis: A study of 40 patients
Tushar B Patil1, Madhuri M Paithankar2
1 Department of Medicine, MNR Medical College, Sangareddy, Andhra Pradesh, India
2 Department of Medicine, Government Medical College, Nagpur, Maharashtra, India
Correspondence Address:
Tushar B Patil
Plot no. 9, Rashtrasant Nagar, Godhani Road, Zingabai Takli, Nagpur, Maharashtra - 440 030
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/1755-6783.77186
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Aims: This study was aimed to study the clinical and radiological profile of neurocysticercosis and outcomes of treatment in neurocysticercosis. Settings and Design: A prospective observational study conducted in a tertiary care hospital. Subjects and Methods: Forty patients coming under Definitive or Probable Diagnosis of neurocysticercosis as per the revised diagnostic criteria for neurocysticercosis were included in this study. Cinical history, physical examination and neuroimaging [computed tomography (CT) or magnetic resonance imaging (MRI)] studies were done at the beginning. Patients were treated with albendazole, corticosteroids and antiepileptic drugs. They were followed up clinically for 3 months and neuroimaging study was repeated 3 months after albendazole therapy. Results: Definitive cases were 28 (70%) and probable cases were 12 (30%). Male:female ratio was 2.07. Mean age of 29.62 ± 9.08 years. The commonest presentation was seizures in 38 (95%); 29 (72.5%) patients had a single lesion and 11 (27.5%) had multiple lesions in initial imaging study. Commonest site of lesion was parietal lobe (45%). Most common stage of presentation was colloidal (55%). Thirty-seven (92.5%) patients were free of seizures at the end of 3 months. At the end of 3 months, 23 (57.5%) patients had radiological resolution (complete resolution + partial resolution + calcification). Conclusions: Neurocysticercosis usually affects young persons, mostly in the third decade, being equally common among vegetarians. Most common clinical manifestation is seizures. Single lesion is more common than multiple lesions, commonly presenting in colloidal stage. Clinical and radiological response to 4 weeks therapy with albendazole is quite satisfactory. All cases of young and adult onset epilepsy in tropical countries should be investigated for neurocysticercosis. |
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