Annals of Tropical Medicine and Public Health
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Year : 2012  |  Volume : 5  |  Issue : 3  |  Page : 199-205

Clinico-laboratory study on filarial lymphoedema

1 Department of Internal Medicine, Faculty of Medicine, Mansoum University Hospitals, Mansoura, Egypt
2 Department of Parasitology, Faculty of Medicine, Mansoum University Hospitals, Mansoura, Egypt
3 Department of Vascular Surgery, Faculty of Medicine, Mansoum University Hospitals, Mansoura, Egypt

Correspondence Address:
Mohamad A Ebrahim
Department of Internal Medicine, Islamic University Hospital, Al-Madinah Al-Munawarah, Kingdom of Saudi Arabia

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Source of Support: None, Conflict of Interest: None

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Context: Lymphatic filariasis is considered the second leading cause of permanent physical disability in humans next to mood disorder. Aims: To evaluate filarial lymphoedema as a considerable burden to patients and the community. Settings and Design: This study was conducted on 45 patients with filarial lymphoedema among 2,350 patients with lower limb edema and 22 age- and sex-matched controls, from May 2005 to May 2008. Materials and Methods: Subjects were subjected to full history taking, clinical examination, Doppler ultrasound on the affected leg, laboratory tests for filariasis. Statistical Analysis: Data were analyzed using the Statistical Package for Social Scientist (SPSS) for windows 7.5. (SPSS Inc, Chicago, USA). Results: Male to female ratio was approximately 1:1.8. The age group 21-30 years was more affected (42%). The majority of cases of filarial lymphoedema in the present study were diagnosed in advanced irreversible stages. Five patients had hydrocele. Four cases (8.9%) were detected to be microfilaremic, 60% of cases were positive for Immunoglobulin (Ig) G, 4.44% were IgM positive and positive cases for filarial antigenemia were 64.4%. Conclusion: The majority of cases in the present study were detected in advanced irreversible stages with patient disability and serious socioeconomic impact.

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