Annals of Tropical Medicine and Public Health
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Year : 2012  |  Volume : 5  |  Issue : 3  |  Page : 236-239

Case fatality rate of leptospirosis in a tertiary care hospital in Kerala, India

Department of Community Medicine, M.O S.C Medical College, Kolenchery, Ernakulam, Kerala, India

Correspondence Address:
Jimmy Antony
Department of Community Medicine, M.O.S.C Medical College, Kolenchery, Ernakulam, Kerala - 682 311
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1755-6783.98626

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Context: Leptospirosis is under-reported because of its wide spectrum of signs and symptoms. The infection mainly occurs in farmers and individuals involved in water-related jobs and activities and it can be 100 times more frequent in tropical areas. Aim : The present hospital-based study was conducted in an endemic area of tropical country to find out the case fatality of this disease over time, age, and sex. Settings and Design : It was a hospital-based retrospective study of five years conducted in a tertiary care hospital in Kerala, India. Materials and Methods : The data were collected from registers maintained in the medical records department and analysed by using Microsoft excel. Statistical Analysis : Chi-square and 'Z' tests were applied for the comparison of proportions. Results : Of the 1,523 confirmed cases, 993 (65.20%) were male and 530 (33.02%) were female. Of the confirmed cases, 63 died: 44 (69.84%) male and 19 (30.15%) female. The case fatality of leptospirosis was 4.13%, and it was high in the age group 40-60 years in both sexes. Of the 63 deaths, 20 (31.74%) were due to multiple organ dysfunction and 12 (19.04%) due to renal failure. The case fatality rate was high in males and it increased with age in both sexes. The case fatality rate of leptospirosis varied in the age groups <20 and ≥60 years, which were 1.22% and 19.32%, respectively. The case fatality of males was 4.43% and of females it was 3.58%. Conclusion : It was suggested that effective leptospirosis control in endemic areas needs a multifactorial approach.

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