Annals of Tropical Medicine and Public Health
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Year : 2014  |  Volume : 7  |  Issue : 6  |  Page : 268
The newest H10N8 influenza: It is still a story of neurological problem due to new emerging influenzas

1 Wiwanitkit House, Bangkhae, Bangkok, Thailand
2 Hainan Medical University, Haikou, China; University of Nis, Serbia; Joseph Ayo Babalola University, Nigeria

Click here for correspondence address and email

Date of Web Publication14-Apr-2015

How to cite this article:
Wiwanitkit S, Wiwanitkit V. The newest H10N8 influenza: It is still a story of neurological problem due to new emerging influenzas. Ann Trop Med Public Health 2014;7:268

How to cite this URL:
Wiwanitkit S, Wiwanitkit V. The newest H10N8 influenza: It is still a story of neurological problem due to new emerging influenzas. Ann Trop Med Public Health [serial online] 2014 [cited 2021 Apr 11];7:268. Available from:
Dear Sir,

Within the past few years, there have been many new emerging influenza infections that have led to global concern over a possible worldwide pandemic. Focusing on the clinical presentations of these new emerging influenza infections, atypical extrarespiratory tract presentations can be seen that have under the focus in medicine. The neurological presentation of new emerging influenzas is very interesting. Focusing on the recently emerging H7N9 influenza, many cases with neurological problems can be seen. [1],[2] The newest emerging H10N8 influenza has just been reported from China. The neurological problem in the indexed cases with this new emerging influenza is of interest and should be discussed. [3],[4],[5] Historically, the first case of H10N8 was observed in December 2013 in China. The patient was a 73-year-old woman who initially presented with flu-like syndrome. [3],[4],[5] This patient ended up with a multiple organ failure syndrome and died on day 9 after hospitalization. [3],[4],[5] In this case, the patient had several underlying conditions such as hypertension and coronary heart disease, and she also got a recent thymectomy for myasthenia gravis treatment. [3],[4],[5] This patient was under immunossupressive medication. [3],[4],[5] In this case, the patient showed a decreased level of consciousness that may have been a sign of a neurological condition. However, this finding may have been nonspecific since it could be an obvious finding in patients with multiple organ failure syndrome. After this case, there were two other cases out of whom, one died after hospitalization. Focusing on the other death case, the same clinical findings including alteration of consciousness could be observed. [3],[4],[5] Despite the fact that other influenza viruses have been associated with neurological problems, the present evidence on neurological problem is still inconclusive. It is still questionable whether H10N8 has a bearing on the central nervous system (CNS) or not. Nevertheless, it should be kept in mind that the new emerging H10N8 influenza infection might induce neurological problem. To answer the existing myth, close monitoring and further research on the exact pathogenesis focusing on the possibility of neuropathology of this new infection is recommended.

   References Top

Wiwanitkit V. Neurological manifestation in new emerging H7N9 Influenza: An issue in neurology. Acta Neurol Taiwan 2013;22:138-9.  Back to cited text no. 1
Wiwanitkit S, Wiwanitkit V. Brain involvement in H7N9 bird flu: A topic for consideration. Arq Neuropsiquiatr 2013;71:825.  Back to cited text no. 2
To KK, Tsang AK, Chan JF, Cheng VC, Chen H, Yuen KY. Emergence in China of human disease due to avian influenza A(H10N8) - cause for concern? J Infect 2014;68:205-15.  Back to cited text no. 3
Chen H, Yuan H, Gao R, Zhang J, Wang D, Xiong Y, et al. Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: A descriptive study. Lancet 2014;383:714-21.  Back to cited text no. 4
García-Sastre A, Schmolke M. Avian influenza A H10N8 - a virus on the verge? Lancet 2014;383:676-7.  Back to cited text no. 5

Correspondence Address:
Somsri Wiwanitkit
Wiwanitkit House, Bang Khae, Bangkok - 10160
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1755-6783.155022

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