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| Year : 2017 | Volume
: 10
| Issue : 2 | Page : 483-484 |
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| Peptide similarity, but no structure similarity: Can it explain the autoimmunity theory for pathology in Zika virus infection |
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Won Sriwijitalai1, Viroj Wiwanitkit2
1 RVT Medical Center, Bangkok, Thailand
2 Department of Tropical Medicine, Hainan Medical University, Hainan, China
Click here for correspondence address and email
| Date of Web Publication | 22-Jun-2017 |
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How to cite this article:
Sriwijitalai W, Wiwanitkit V. Peptide similarity, but no structure similarity: Can it explain the autoimmunity theory for pathology in Zika virus infection. Ann Trop Med Public Health 2017;10:483-4 |
How to cite this URL:
Sriwijitalai W, Wiwanitkit V. Peptide similarity, but no structure similarity: Can it explain the autoimmunity theory for pathology in Zika virus infection. Ann Trop Med Public Health [serial online] 2017 [cited 2021 Jan 24];10:483-4. Available from: https://www.atmph.org/text.asp?2017/10/2/483/196858 |
Dear Sir,
Zika virus infection is the big problem at present. There is a new theory that autoimmunity leads to the main pathology in Zika virus infection. It is proposed that microcephaly and Guillain–Barré syndrome are important problems in Zika virus infection [1] Peptides' sharing is mentioned in that report.[1] However, hereby we further tried to predict the structure of the mentioned peptides using structural genomics and found that there is no structural similarity among the mentioned peptides. The explanation of the autoimmunity-based pathology in Zika virus infection is against this observation, and further study on this topic is recommended.
Financial support and sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
 References | |  |
| 1. | Lucchese G, Kanduc D. Zika virus and autoimmunity: From microcephaly to Guillain-Barré syndrome, and beyond. Autoimmun Rev 2016. pii: S1568-997230077-5.  |
Correspondence Address:
Won Sriwijitalai
RVT Medical Center, Bangkok
Thailand
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/1755-6783.196858
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