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Sriwijitralai W, Wiwanitkit V. Rebound thrombocytosis and persistence of clinical symptoms after recovery from dengue hemorrhagic fever. Ann Trop Med Public Health 2017;10:286
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Sriwijitralai W, Wiwanitkit V. Rebound thrombocytosis and persistence of clinical symptoms after recovery from dengue hemorrhagic fever. Ann Trop Med Public Health [serial online] 2017 [cited 2017 Jul 15];10:286. Available from: https://www.atmph.org/text.asp?2017/10/1/286/205577
The clinical problems of dengue include an acute febrile illness and decreasing platelet count. The management of the patient is by having a good fluid replacement therapy until the recovery of platelet count. Nevertheless, sometimes, there can be problematic situations after the complete recovery of platelet count. Here, the authors present an exemplary case of rebound thrombocytosis and persistence of clinical symptoms after recovery from dengue hemorrhagic fever. The patient is a 19-year-old female. The patient was just diagnosed of dengue hemorrhagic fever 10 days before and had fluid replacement therapy until the recovery of platelet count (platelet count at first diagnosis of dengue = 50,000/μL; at recovery – Day 7th = 190,000/μL). However, this case still had the problem of myalgia and arthralgia, hence, returned to the physician. Repeated examination showed platelet count equal to 500,000/μL. This case was closely followed up for another 1 week, and the platelet count returned to normal (200,000/μL) but the myalgia and arthralgia problem still existed. This case is an example of rebound thrombocytosis., It is not commonly documented and it can result in poor outcome such as myocardial infarction. In addition, in the present case, the persistence of clinical symptoms is also observed. This is also a less mentioned issue in postdengue care. According to the study by García et al., dengue symptoms can last upto 2 years. Follow up is recommended for those cases.
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