Helicobacter pylori infection and its possible controlling public health measures at the present times

How to cite this article:
Tavana MA. Helicobacter pylori infection and its possible controlling public health measures at the present times. Ann Trop Med Public Health 2009;2:32


How to cite this URL:
Tavana MA. Helicobacter pylori infection and its possible controlling public health measures at the present times. Ann Trop Med Public Health [serial online] 2009 [cited 2020 Dec 5];2:32. Available from: https://www.atmph.org/text.asp?2009/2/1/32/64277


Helicobacter pylori is is a Gram-negative, spiral shaped, microaerophilic bacterium that can colonize epithelial cells of the stomach and plays an important role in the pathogenesis of chronic gastritis, peptic ulcer disease, and, possibly, gastric carcinoma. [1] H. pylori infects the majority of the adult population in the world in particular in developing countries [Figure 1]. It has to be said that the prevalence rate of infection in different population may be different up to many epidemiological factors (diet, genetic). According to serology data in Asia, the prevalence rate is high in particular in Korea and Japan. [2] However, specific guidelines may be needed for the management of infection in different regions based on disease patterns. [3] Still we need to know whether H. pylori infection may be beneficial in certain circumstances and whether eradicating the infection may be disadvantageous to some subjects. [4] Vaccines are being tested in animals and humans. Despite many clinical trials, it is very early days yet. At the present point in time, there are no vaccines for the prevention of H. pylori. [5] It could be concluded that preventive efforts and particularly screening are useful in order to find out the susceptible cases. The association between gastro-oesophageal reflux disease and irritable bowel syndrome was significantly higher in our community compared with others. [6] Clarithromycin resistance was seen for H. pylori recently. [7] Smoking may benefit peptic ulcer patients with H. pylori infection. [8] New research in the future must be performed to find out different aspects of this question.



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2. Tokudome S, Ando R, Ghadimi R, Tanaka T, Hattori N, Yang Z, et al. Are there any real Helicobacter pylori infection-negative gastric cancers in Asia? Asian Pac J Cancer Prev 2007;8:462-3.
3. Day AS, Mitchell HM, Bohane TD. Management guidelines for Helicobacter pylori infection: Utilization by paediatric gastroenterologists in Australasia. J Paediatr Child Health 2004;40:195-200.
4. McColl KE. What remaining questions regarding Helicobacter pylori and associated diseases should be addressed by future research? View from Europe. Gastroenterology 1997;113:158-62.
5. Agusztyn-Krynicka EK, Godlewska R. New approaches for Helicobacter vaccine development–difficulties and progress. Pol J Microbiol 2008;57:3-9.
6. Solhpour A, Pourhoseingholi MA, Soltani F, Zarghi A, Solhpour A, Habibi M, Gastro-oesophageal reflux disease and irritable bowel syndrome: A significant association in an Iranian population. Eur J Gastroenterol Hepatol 2008;20:719-25.
7. Kawai T, Kawakami K, Kataoka M, Itoi T, Takei K, Moriyasu F, et al. A study of the relationship between Helicobacter pylori microbial susceptibility, 13C-urea breath test values. Hepatogastroenterology 2008;55:786-90.
8. Pillay KV, Htun M, Naing NN, Norsa’adah B. Helicobacter pylori infection in peptic ulcer disease: The importance of smoking and ethnicity. Southeast Asian J Trop Med Public Health 2007;38:1102-10.

Source of Support: None, Conflict of Interest: None




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