Sixth human malarial species: It becomes the new challenge in malariology

How to cite this article:
Wiwanitkit S, Wiwanitkit V. Sixth human malarial species: It becomes the new challenge in malariology. Ann Trop Med Public Health 2016;9:123-4


How to cite this URL:
Wiwanitkit S, Wiwanitkit V. Sixth human malarial species: It becomes the new challenge in malariology. Ann Trop Med Public Health [serial online] 2016 [cited 2020 Aug 6];9:123-4. Available from:

Dear Sir,

Malaria is still the global public health issue. Thousands of infections can be seen around the tropical world in each year. General practitioner might be familiar with four classical malarial species – vivax, falciparum, malariae, and ovale. However, there are new reports on the new malarial species in human beings. The recent emerging of the fifth malarial species, knowlesi, becomes a big issue in malariology.­ [1] This new malaria was firstly observed in Asia, and it is already accepted as the emerging important malaria in the present day. [2] However, the fifth malarial species is not the newest species. In 2014, the sixth malaria species, cynomolgi, was already reported. [3] Natural human infection has never been reported before the first case report by Ta et al[3] The first case report is from Malaysia that is initially misdiagnosed as knowlesi malaria. [3] Basically, cynomolgi is very similar to vivax and can be misdiagnosed. [4] Ta et al. noted “Plasmodium cynomolgi is morphologically indistinguishable from P. vivax, and one of the most used PCR methods for malaria infection detection may identify a P. cynomolgi infection as P. vivax.” [3] The zoonotic malaria is an actual hot issue in the present day. [5] It is the time that practitioner has to refresh their knowledge in diagnosis of an old disease, malaria.

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Servonnet A, Rapp C, Delacour H, Bigaillon C, Pilo JE, Mérens A. Plasmodium knowlesi: An emerging species in humans. Med Sante Trop 2012;22:417-21.
Wiwanitkit V. Plasmodium knowlesi malarial infection in western travelers returning from Southeast Asia. A summary of the clinical pattern. Arch Hellenic Med 2012;29:58-60.
Ta TH, Hisam S, Lanza M, Jiram AI, Ismail N, Rubio JM. First case of a naturally acquired human infection with Plasmodium cynomolgi. Malar J 2014;13:68.
Huang YM. Progress on the study of the distribution of Plasmodium cynomolgi in the world. Zhonghua Yu Fang Yi Xue Za Zhi 1994;28: 49-50.
Ramasamy R. Zoonotic malaria – global overview and research and policy needs. Front Public Health 2014;2:123.

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1755-6783.177383

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